Literature DB >> 23435386

Switchable delivery of small interfering RNA using a negatively charged pH-responsive polyethylenimine-based polyelectrolyte complex.

S-Ja Tseng1, Yi-Fang Zeng, Yu-Fan Deng, Pan-Chyr Yang, Je-Ruei Liu, Ivan M Kempson.   

Abstract

A small interfering RNA (siRNA)-loaded polyelectrolyte constructed with branched polyethylenimine (bPEI) and copolymers, consisting of polyethylene glycol (PEG), histidine (His), and glutamic acid (Glu), was developed in order to provide a tumor acidosis-triggered delivery system with low cytotoxicity.

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Year:  2013        PMID： 23435386     DOI： 10.1039/c3cc00134b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Anionic Polymer and Quantum Dot Excipients to Facilitate siRNA Release and Self-Reporting of Disassembly in Stimuli-Responsive Nanocarrier Formulations.

Authors:  Chad T Greco; Jason C Andrechak; Thomas H Epps; Millicent O Sullivan
Journal:  Biomacromolecules       Date:  2017-05-10       Impact factor: 6.988

2.  Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour.

Authors:  S-Ja Tseng; Zi-Xian Liao; Shih-Han Kao; Yi-Fang Zeng; Kuo-Yen Huang; Hsin-Jung Li; Chung-Lin Yang; Yu-Fan Deng; Chi-Feng Huang; Shuenn-Chen Yang; Pan-Chyr Yang; Ivan M Kempson
Journal:  Nat Commun       Date:  2015-03-05       Impact factor: 14.919

Review 3.  Charge-reversal nanoparticles: novel targeted drug delivery carriers.

Authors:  Xinli Chen; Lisha Liu; Chen Jiang
Journal:  Acta Pharm Sin B       Date:  2016-06-08       Impact factor: 11.413

4.  Release of Doxorubicin by a Folate-Grafted, Chitosan-Coated Magnetic Nanoparticle.

Authors:  Chung-Lin Yang; Jyh-Ping Chen; Kuo-Chen Wei; Ju-Yu Chen; Chia-Wen Huang; Zi-Xian Liao
Journal:  Nanomaterials (Basel)       Date:  2017-04-13       Impact factor: 5.076
  4 in total

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