Literature DB >> 23434619

Tissue voltage discordance during tachycardia versus sinus rhythm: implications for catheter ablation.

Jason S Bradfield1, William Huang, Roderick Tung, Eric Buch, Jean-Phillip Okhovat, Osamu Fujimura, Noel G Boyle, Jeffrey Gornbein, Kenneth A Ellenbogen, Kalyanam Shivkumar.   

Abstract

BACKGROUND: Electroanatomic mapping systems are an important tool to identify cardiac chamber voltage and assess channels of slow conduction.
OBJECTIVE: To assess the correlation between electroanatomic mapping voltage maps obtained during macroreentrant tachycardia compared to sinus rhythm (SR) with a contact mapping system.
METHODS: We retrospectively evaluated patients with atrial flutter (AFL) referred for radiofrequency ablation with electroanatomic voltage maps obtained during AFL and SR. The atrium was divided into predetermined segments. Overall atrial and segmental peak-to-peak bipolar voltages in AFL and SR were assessed. To directly compare a region within the same patient, tissue voltage differences during AFL and SR were assessed on the basis of mean voltage difference.
RESULTS: Sixteen patients (87% men) had available voltage maps. Eighty-one percent had typical cavotricuspid isthmus-dependent right AFL. A mean of 441.7±153.9 vs 398.1±125.4 total points (P = .22) were sampled during AFL and SR, with a mean of 99.5±58.9 vs 91.2±60.4 points (P = .45) sampled per region. Overall right atrial mean voltage was significantly higher during AFL than SR (0.554±0.092mV vs 0.473±0.079mV; P≤.001), with the lateral wall (0.707±0.120mV vs 0.573±0.097mV; P = .0004) and the cavotricuspid isthmus (0.559±0.100mV vs 0.356±0.066mV; P<.0001) also showing higher mean voltage during AFL. When compared within an individual patient, 19% (14 of 75) of the patient regions had a>0.5mV mean voltage difference and 40% (30 of 75) had a>0.25mV mean voltage difference.
CONCLUSIONS: These data suggest that voltage maps performed during macroreentrant atrial arrhythmias often vary significantly from maps obtained during SR.
Copyright © 2013 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23434619     DOI: 10.1016/j.hrthm.2013.02.020

Source DB:  PubMed          Journal:  Heart Rhythm        ISSN: 1547-5271            Impact factor:   6.343


  5 in total

Review 1.  Arrhythmia Mechanisms Revealed by Ripple Mapping.

Authors:  George Katritsis; Vishal Luther; Prapa Kanagaratnam; Nick Wf Linton
Journal:  Arrhythm Electrophysiol Rev       Date:  2018-12

2.  Voltage during atrial fibrillation is superior to voltage during sinus rhythm in localizing areas of delayed enhancement on magnetic resonance imaging: An assessment of the posterior left atrium in patients with persistent atrial fibrillation.

Authors:  Norman A Qureshi; Steven J Kim; Chris D Cantwell; Valtino X Afonso; Wenjia Bai; Rheeda L Ali; Matt J Shun-Shin; Louisa C Malcolme-Lawes; Vishal Luther; Kevin M W Leong; Elaine Lim; Ian Wright; Szabi Nagy; Sajad Hayat; Fu Siong Ng; Michael Koa Wing; Nick W F Linton; David C Lefroy; Zachary I Whinnett; D Wyn Davies; Prapa Kanagaratnam; Nicholas S Peters; Phang Boon Lim
Journal:  Heart Rhythm       Date:  2019-06-03       Impact factor: 6.343

Review 3.  Left atrial voltage mapping: defining and targeting the atrial fibrillation substrate.

Authors:  Iain Sim; Martin Bishop; Mark O'Neill; Steven E Williams
Journal:  J Interv Card Electrophysiol       Date:  2019-05-10       Impact factor: 1.900

4.  The effect of activation rate on left atrial bipolar voltage in patients with paroxysmal atrial fibrillation.

Authors:  Steven E Williams; Nick Linton; Louisa O'Neill; James Harrison; John Whitaker; Rahul Mukherjee; Christopher A Rinaldi; Jaswinder Gill; Steven Niederer; Matthew Wright; Mark O'Neill
Journal:  J Cardiovasc Electrophysiol       Date:  2017-09

5.  Intra-Atrial Conduction Delay Revealed by Multisite Incremental Atrial Pacing is an Independent Marker of Remodeling in Human Atrial Fibrillation.

Authors:  Steven E Williams; Nick W F Linton; James Harrison; Henry Chubb; John Whitaker; Jaswinder Gill; Christopher A Rinaldi; Reza Razavi; Steven Niederer; Matthew Wright; Mark O'Neill
Journal:  JACC Clin Electrophysiol       Date:  2017-09
  5 in total

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