Literature DB >> 23434429

TCTP/HRF pathway and angiogenesis: a feasible intercourse in chronic lymphocytic leukemia.

Münci Yağcı1, Zeynep Arzu Yegin, Nalan Akyürek, Handan Kayhan, Zübeyde Nur Ozkurt, Gülsan Türköz Sucak, Rauf Haznedar.   

Abstract

This prospective study was planned to determine the intercourse between translationally controlled tumor protein (TCTP)/histamine releasing factor (HRF)/histamine pathway and angiogenesis in chronic lymphocytic leukemia (CLL). A total of 153 CLL patients were included. Serum histamine levels were higher in CLL patients. A positive correlation was found between microvessel density (MVD)-mast cell (MC) count; MVD-TCTP/HRF and MC count-TCTP/HRF. Microvessel density, MC and ZAP 70 were significantly higher in TCTP/HRF-positive group. Time to first treatment was shorter in patients with increased MVD and TCTP/HRF. Further data is essential to ascertain the role of TCTP/HRF pathway in tumor angiogenesis and CLL prognosis.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23434429     DOI: 10.1016/j.leukres.2013.01.005

Source DB:  PubMed          Journal:  Leuk Res        ISSN: 0145-2126            Impact factor:   3.156


  3 in total

Review 1.  Signaling and molecular basis of bone marrow niche angiogenesis in leukemia.

Authors:  R Shirzad; S Shahrabi; A Ahmadzadeh; K R Kampen; M Shahjahani; N Saki
Journal:  Clin Transl Oncol       Date:  2016-01-07       Impact factor: 3.405

2.  A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy.

Authors:  Nicolas Fischer; Ean-Jeong Seo; Sara Abdelfatah; Edmond Fleischer; Anette Klinger; Thomas Efferth
Journal:  Invest New Drugs       Date:  2021-01-25       Impact factor: 3.850

3.  Function of translationally controlled tumor protein (TCTP) in Eudrilus eugeniae regeneration.

Authors:  Elaiya Raja Subramanian; Nino Gopi Daisy; Dinesh Kumar Sudalaimani; Kalidas Ramamoorthy; Subburathinam Balakrishnan; Jackson Durairaj Selvan Christyraj; Vaithilingaraja Arumugaswami; Sudhakar Sivasubramaniam
Journal:  PLoS One       Date:  2017-04-12       Impact factor: 3.240

  3 in total

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