| Literature DB >> 23433051 |
Hossein Hosseinzadeh1, Mohsen Tafaghodi, Mojdeh Jalal Mosavi, Elahe Taghiabadi.
Abstract
Nigella sativa L. is used as a galactagogue in traditional medicine. Hence, the effects of aqueous and ethanolic extracts of N. sativa seeds on milk production in rats were evaluated. The measurement of milk production was by measuring pup weight during suckling period. The intraperitoneal LD(50) values of aqueous and ethanolic extracts of N. sativa were 4.23 and 4.9 g/kg, respectively. The aqueous (0.5 g/kg) and ethanolic extracts (1 g/kg) increased milk production significantly (p < 0.001), producing about 31.3% and 37.6% more milk than control, respectively. During the study period, the pups gained weight with the aqueous (0.5 g/kg, p < 0.01) and ethanolic extracts (1 g/kg, p < 0.05). It is concluded that aqueous and ethanolic extracts of N. sativa can stimulate milk production in rats.Entities:
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Year: 2012 PMID： 23433051 DOI： 10.1016/j.jams.2012.07.019
Source DB: PubMed Journal: J Acupunct Meridian Stud ISSN： 2005-2901