Literature DB >> 23432985

Predominance of females with oesophageal cancer in Gezira, Central Sudan.

Moawia Elbalal Mohammed1, Daffala O Abuidris, Elgaili M Elgaili, Nagla Gasmelseed.   

Abstract

BACKGROUND: The majority of oesophageal cancer cases occur in developing countries. Globally males predominate.
OBJECTIVE: This study aims to review the clinical aspects of oesophageal carcinoma in Sudanese patients referred to endoscopy in Gezira, Central Sudan. PATIENTS &
METHOD: Data were collected from patients who underwent endoscopy during the period from 2005 to 2007 at The Gezira Centre for Gastroenterology Endoscopies and Laparoscopic Surgery. Demographic and clinical data including; sex, age, locality of residence, clinical presentation, tumour site and morphology were collected and analysed.
RESULTS: Seven hundred and two patients were consecutively referred to our centre for endoscopy. Seventy-three out of 702 patients (9.6%) referred for endoscopy proved to have oesophageal cancer. Fifty-five out of 73 patients (75.3%) were females generating a male to female ratio of 1:3.3. The mean age of females was 52.75±11.66years and that of males was 66.11±9.52. Sixteen (21.9%) patients came from the Managil; 14 (19.2%) from Hasaheesa and Rufaa; 14 (19.2%) from Blue Nile; 10 (13.7%) from Wadmedani (Central Sudan) and 19 (26%) from Elfaw and Kassala. In most cases (75.3%), the tumours were located in the middle third of the oesophagus. 79.5% of the tumours were squamous cell type.
CONCLUSION: Patients referred for endoscopy to The Gezira Centre for Gastroenterology, Endoscopies and Laparoscopic Surgery in Gezira revealed a greater proportion of women than of men diagnosed with the disease (1:3.3). More studies are needed to investigate the epidemiology of this disease and to identify the reason for the apparent gender uneven manifestation.
Copyright © 2012 Arab Journal of Gastroenterology. Published by Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 23432985     DOI: 10.1016/j.ajg.2012.06.012

Source DB:  PubMed          Journal:  Arab J Gastroenterol        ISSN: 1687-1979            Impact factor:   2.076


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