Linda Grace Roy1, Manjunath S Shetty, Asna Urooj. 1. Department of Studies in Food Science and Nutrition, University of Mysore, Mysore-570 006, Karnataka, India. linsroy@gmail.com
Abstract
OBJECTIVE: To formulate a nutrient supplement using low cost, commonly available food ingredients and test its efficacy on various nutritional parameters in haemodialysis (HD) subjects. DESIGN: Prospective intervention study. SUBJECTS: 15 subjects who did not have diabetes were recruited for the study. The subjects served as self controls. APPROACH: The subjects received a multi-nutrient formulation for a period of 3 months. Somatic status [weight, mid upper arm circumference (MUAC), mid upper arm muscle circumference (MUAMC), waist and hip measurements], biochemical parameters [blood urea nitrogen (BUN), total iron binding capacity (TIBC),serum levels of creatinine, albumin, triglycerides, sodium, potassium, calcium, phosphorus and high sensitive C-reactive protein(HsCRP)], dietary intake and malnutrition inflammation score (MIS) were assessed. RESULTS: Significant increments (P ≤ 0.01) in anthropometric measurements. Significant increases (P ≤ 0.01) in Hb, BUN, serum creatinine, albumin and total protein and a significant decrease (P ≤ 0.01) in HsCRP and MIS were observed at the end of the study. An increase in baseline food/nutrient intake was also observed. CONCLUSION: Nutritional supplementation designed for haemodialysis, improved their nutritional status in the short term study.
OBJECTIVE: To formulate a nutrient supplement using low cost, commonly available food ingredients and test its efficacy on various nutritional parameters in haemodialysis (HD) subjects. DESIGN: Prospective intervention study. SUBJECTS: 15 subjects who did not have diabetes were recruited for the study. The subjects served as self controls. APPROACH: The subjects received a multi-nutrient formulation for a period of 3 months. Somatic status [weight, mid upper arm circumference (MUAC), mid upper arm muscle circumference (MUAMC), waist and hip measurements], biochemical parameters [blood ureanitrogen (BUN), total iron binding capacity (TIBC),serum levels of creatinine, albumin, triglycerides, sodium, potassium, calcium, phosphorus and high sensitive C-reactive protein(HsCRP)], dietary intake and malnutrition inflammation score (MIS) were assessed. RESULTS: Significant increments (P ≤ 0.01) in anthropometric measurements. Significant increases (P ≤ 0.01) in Hb, BUN, serum creatinine, albumin and total protein and a significant decrease (P ≤ 0.01) in HsCRP and MIS were observed at the end of the study. An increase in baseline food/nutrient intake was also observed. CONCLUSION: Nutritional supplementation designed for haemodialysis, improved their nutritional status in the short term study.
Authors: Jessica M Quimby; Kellyi K Benson; Stacie C Summers; Ashlie Saffire; Andrea K Herndon; Shasha Bai; Daniel L Gustafson Journal: J Feline Med Surg Date: 2019-06-04 Impact factor: 2.015