Literature DB >> 23431964

Two new sesquiterpenoids from the rhizomes of Nardostachys jatamansi.

K Rekha1, R Ranga Rao, Richa Pandey, Kothakonda Rajendra Prasad, Katragadda Suresh Babu, Janakiram R Vangala, Sashi V Kalivendi, Janaswamy Madhusudana Rao.   

Abstract

Phytochemical investigation of CHCl(3):MeOH (1:1) extract from the rhizomes of Nardostachys jatamansi led to the isolation of two new sesquiterpenoids (5 and 6), along with six known compounds (1-4, 7, and 8). The structures of two new compounds were established using IR, MS, 1D, and 2D NMR techniques. In addition, all the isolates were tested for their cytotoxicities against the A549 (lung cancer), DU-145 (prostate cancer), MCF-7 (breast cancer), and SK-N-SH (neuroblastoma).

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Year:  2013        PMID: 23431964     DOI: 10.1080/10286020.2012.738673

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  4 in total

1.  Evaluation of antioxidant and anticancer activity of extract and fractions of Nardostachys jatamansi DC in breast carcinoma.

Authors:  Shilpee Chaudhary; Kodangala Subraya Chandrashekar; Karkala Sreedhara Ranganath Pai; Manganahalli Manjunath Setty; Raviraj Anand Devkar; Neetinkumar Dnyanoba Reddy; Muhammed Haneefa Shoja
Journal:  BMC Complement Altern Med       Date:  2015-03-10       Impact factor: 3.659

Review 2.  Plant Species of Sub-Family Valerianaceae-A Review on Its Effect on the Central Nervous System.

Authors:  Gitishree Das; Han-Seung Shin; Rosa Tundis; Sandra Gonçalves; Ourlad Alzeus G Tantengco; Maria G Campos; Rosaria Acquaviva; Giuseppe Antonio Malfa; Anabela Romano; Joyce Ann H Robles; Mariel Q Clores; Jayanta-Kumar Patra
Journal:  Plants (Basel)       Date:  2021-04-22

3.  Narjatamanins A and B, a pair of novel epimers possessing a 2,3-seco-iridoid skeleton with an unusual 1,10-oxygen bridge from Nardostachys jatamansi and evaluation of their effects on worm paralysis in AD C. elegans.

Authors:  Ye Zhao; Bing Li; Yi-Fan Yu; Pei-Qian Wu; Chun-Xue Yu; Pan-Jie Su; De-Juan Zhi; Feng-Ming Qi; Dong-Qing Fei; Zhan-Xin Zhang
Journal:  RSC Adv       Date:  2019-08-06       Impact factor: 3.361

4.  BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response.

Authors:  Janakiram R Vangala; Ajay Potluri; Senthil K Radhakrishnan
Journal:  Biomolecules       Date:  2020-03-26
  4 in total

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