Kotaro Hamada1, Kenji Kayashima. 1. Department of Anesthesia, Univesity of Occupational and Environmental Health, Kitakyushu 807-8555.
Abstract
BACKGROUND: In cesarean section, residual neuromuscular blockade is often observed at the end of the operation. Sugammadex (SGX) is a selective relaxant-binding agent which reverses the blockade at any depth in 2-3 minutes. We investigated whether SGX improves the efficient management of operating rooms. METHODS: Thirty-six patients were divided into two groups (Group A: 19 patients before SGX became commercially available, Group B: 17 patients after SGX became available). The dosage of SGX, time to extubate and time to discharge from operating rooms after surgery were extracted from anesthetic records retrospectively. RESULTS: The mean dosage of SGX was 192 mg in 15 of the 17 patients in group B. Eight of the 19 patients in group A were extubated within 30 minutes. Five of the 19 were not extubated in the operating rooms. All 17 in group B were extubated within 30 minutes in the operating rooms. CONCLUSIONS: SGX decreased the time to extubation after cesarean section under general anesthesia after surgery, and could improve the efficient management of operating rooms.
BACKGROUND: In cesarean section, residual neuromuscular blockade is often observed at the end of the operation. Sugammadex (SGX) is a selective relaxant-binding agent which reverses the blockade at any depth in 2-3 minutes. We investigated whether SGX improves the efficient management of operating rooms. METHODS: Thirty-six patients were divided into two groups (Group A: 19 patients before SGX became commercially available, Group B: 17 patients after SGX became available). The dosage of SGX, time to extubate and time to discharge from operating rooms after surgery were extracted from anesthetic records retrospectively. RESULTS: The mean dosage of SGX was 192 mg in 15 of the 17 patients in group B. Eight of the 19 patients in group A were extubated within 30 minutes. Five of the 19 were not extubated in the operating rooms. All 17 in group B were extubated within 30 minutes in the operating rooms. CONCLUSIONS:SGX decreased the time to extubation after cesarean section under general anesthesia after surgery, and could improve the efficient management of operating rooms.