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Literature DB >> 23430024

Reading the tea leaves of tumor-mediated immunosuppression.

Abstract

Polyphenol E, available as Polyphenon E, is a green tea extract whose activity can be benchmarked to the presence of specific catechins such as epigallocatechin 3-gallate (EGCG). Herein, Polyphenon E is shown to reverse myeloid-derived suppressor cell activity, linking the activity of a natural product extract to cell-mediated immunity. ©2012 AACR.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Polyphenols
Tea

Year: 2013 PMID： 23430024 PMCID： PMC3594479 DOI： 10.1158/1078-0432.CCR-12-3792

Source DB: PubMed Journal: Clin Cancer Res ISSN： 1078-0432 Impact factor: 12.531

12 in total

Review 1. Macrophage plasticity and polarization: in vivo veritas.

Authors: Antonio Sica; Alberto Mantovani
Journal: J Clin Invest Date: 2012-03-01 Impact factor: 14.808

2. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells.

Authors: Melissa G Lechner; Daniel J Liebertz; Alan L Epstein
Journal: J Immunol Date: 2010-07-19 Impact factor: 5.422

3. Chemoprevention of human prostate cancer by green tea catechins: two years later. A follow-up update.

Authors: Maurizio Brausi; Federica Rizzi; Saverio Bettuzzi
Journal: Eur Urol Date: 2008-04-04 Impact factor: 20.096

4. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma.

Authors: Chrystal U Louis; Barbara Savoldo; Gianpietro Dotti; Martin Pule; Eric Yvon; G Doug Myers; Claudia Rossig; Heidi V Russell; Oumar Diouf; Enli Liu; Hao Liu; Meng-Fen Wu; Adrian P Gee; Zhuyong Mei; Cliona M Rooney; Helen E Heslop; Malcolm K Brenner
Journal: Blood Date: 2011-10-07 Impact factor: 22.113

5. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha.

Authors: Matthew Kraman; Paul J Bambrough; James N Arnold; Edward W Roberts; Lukasz Magiera; James O Jones; Aarthi Gopinathan; David A Tuveson; Douglas T Fearon
Journal: Science Date: 2010-11-05 Impact factor: 47.728

Review 6. The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity.

Authors: Je-In Youn; Dmitry I Gabrilovich
Journal: Eur J Immunol Date: 2010-11 Impact factor: 5.532

7. Polyphenon [corrected] E enhances the antitumor immune response in neuroblastoma by inactivating myeloid suppressor cells.

Authors: Giorgia Santilli; Izabela Piotrowska; Sandra Cantilena; Olesya Chayka; Marco D'Alicarnasso; Daniel A Morgenstern; Nourredine Himoudi; Katie Pearson; John Anderson; Adrian J Thrasher; Arturo Sala
Journal: Clin Cancer Res Date: 2013-01-15 Impact factor: 12.531

8. Depletion of CD4 T cells enhances immunotherapy for neuroblastoma after syngeneic HSCT but compromises development of antitumor immune memory.

Authors: Weiqing Jing; Jill A Gershan; Bryon D Johnson
Journal: Blood Date: 2009-01-30 Impact factor: 22.113

9. Phase I trial of daily oral Polyphenon E in patients with asymptomatic Rai stage 0 to II chronic lymphocytic leukemia.

Authors: Tait D Shanafelt; Tim G Call; Clive S Zent; Betsy LaPlant; Deborah A Bowen; Michelle Roos; Charla R Secreto; Asish K Ghosh; Brian F Kabat; Mao-Jung Lee; Chung S Yang; Diane F Jelinek; Charles Erlichman; Neil E Kay
Journal: J Clin Oncol Date: 2009-05-26 Impact factor: 44.544