Literature DB >> 23429985

Unraveling the genetics of inhibitors in hemophilia.

Samantha C Gouw1, Karin Fijnvandraat.   

Abstract

In this issue of Blood, Astermark et al have identified novel genetic markers of inhibitory antibody formation in hemophilia patients that may ultimately lead to prediction and even prevention of this severe complication of hemophilia treatment.(1)

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Year:  2013        PMID: 23429985     DOI: 10.1182/blood-2012-12-472647

Source DB:  PubMed          Journal:  Blood        ISSN: 0006-4971            Impact factor:   22.113


  3 in total

1.  Factor VIII gene variants and inhibitor risk in African American hemophilia A patients.

Authors:  Devi Gunasekera; Ruth A Ettinger; Shelley Nakaya Fletcher; Eddie A James; Maochang Liu; John C Barrett; Janice Withycombe; Dana C Matthews; Melinda S Epstein; Richard J Hughes; Kathleen P Pratt
Journal:  Blood       Date:  2015-01-23       Impact factor: 22.113

2.  Maternal microchimerism protects hemophilia A patients from inhibitor development.

Authors:  Yeling Lu; Zhenping Chen; Jing Dai; Xi Wu; Hao Gu; Zekun Li; Jian Li; Qiulan Ding; Wenman Wu; Runhui Wu; Xuefeng Wang
Journal:  Blood Adv       Date:  2020-05-12

3.  High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance.

Authors:  Phuong-Cac T Nguyen; Kenneth B Lewis; Ruth A Ettinger; Jason T Schuman; Jasper C Lin; John F Healey; Shannon L Meeks; Pete Lollar; Kathleen P Pratt
Journal:  Blood       Date:  2014-03-03       Impact factor: 22.113

  3 in total

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