Literature DB >> 23429569

Severe gastrointestinal mucositis following high dose melphalan therapy for multiple myeloma.

Sanjeev Kumar Sharma, Anil Handoo, Dharma Choudhary, Gaurav Dhamija, Nitin Gupta.   

Abstract

Mucositis is a known complication following use of chemotherapy, but fatal mucositis is unusual and management of such cases may be challenging. Pathologically there is denudation of mucosa of gastrointestinal tract. Severe cases can develop ileus and even perforation of bowel wall. We report here a case of multiple myeloma who developed World Health Organization grade 4 gut mucositis following the use of high dose melphalan with the expulsion of "intestine-like" material.

Entities:  

Keywords:  Chemotherapy; Gastrointestinal mucositis

Mesh：

Substances：

Year:  2013        PMID： 23429569      PMCID： PMC3574610          DOI： 10.3748/wjg.v19.i5.784

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN： 1007-9327            Impact factor:   5.742


  5 in total

1.  Incidence and risk factors for lower alimentary tract mucositis after 1529 courses of chemotherapy in a homogenous population of oncology patients: clinical and research implications.

Authors:  Somashekar G Krishna; Weizhi Zhao; Monica L Grazziutti; Naveen Sanathkumar; Bart Barlogie; Elias J Anaissie
Journal:  Cancer       Date:  2010-09-22       Impact factor: 6.860

2.  Management of oral and gastrointestinal mucositis: ESMO Clinical Practice Guidelines.

Authors:  D E Peterson; R-J Bensadoun; F Roila
Journal:  Ann Oncol       Date:  2011-09       Impact factor: 32.976

3.  Oral mucositis in myeloma patients undergoing melphalan-based autologous stem cell transplantation: incidence, risk factors and a severity predictive model.

Authors:  M L Grazziutti; L Dong; M H Miceli; S G Krishna; E Kiwan; N Syed; A Fassas; F van Rhee; H Klaus; B Barlogie; E J Anaissie
Journal:  Bone Marrow Transplant       Date:  2006-10       Impact factor: 5.483

4.  Oral mucositis and outcomes of autologous hematopoietic stem-cell transplantation following high-dose melphalan conditioning for multiple myeloma.

Authors:  Montserrat Vera-Llonch; Gerry Oster; Colleen M Ford; John Lu; Stephen Sonis
Journal:  J Support Oncol       Date:  2007-05

Review 5.  Gastrointestinal and hepatic complications of hematopoietic stem cell transplantation.

Authors:  Hande H Tuncer; Naveed Rana; Cannon Milani; Angela Darko; Samer A Al-Homsi
Journal:  World J Gastroenterol       Date:  2012-04-28       Impact factor: 5.742
  5 in total
  3 in total

1.  GWAS of 972 autologous stem cell recipients with multiple myeloma identifies 11 genetic variants associated with chemotherapy-induced oral mucositis.

Authors:  Elizabeth Ann Coleman; Jeannette Y Lee; Stephen W Erickson; Julia A Goodwin; Naveen Sanathkumar; Vinay R Raj; Daohong Zhou; Kent D McKelvey; Senu Apewokin; Owen Stephens; Carol A Enderlin; Annette Juul Vangsted; Patty J Reed; Elias J Anaissie
Journal:  Support Care Cancer       Date:  2014-09-14       Impact factor: 3.603

2.  Randomized Study of enterade® to Reduce Diarrhea in Patients Receiving High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation.

Authors:  Zachariah De Filipp; Brett Glotzbecker; Laura Luque; Haesook T Kim; Katherine M Mitchell; Samuel N Cheuvront; Robert J Soiffer
Journal:  Asian Pac J Cancer Prev       Date:  2021-01-01

3.  Case report: false positive elevated serum-galactomannan levels after autologous hematopoietic stem cell transplantation caused by oral nutritional supplements.

Authors:  Tobias Rachow; Sebastian Dornaus; Herbert G Sayer; Beate Hermann; Andreas Hochhaus; Marie von Lilienfeld-Toal
Journal:  Clin Case Rep       Date:  2016-04-12
  3 in total

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