Literature DB >> 23429551

What the infectious disease physician needs to know about pegylated interferon and ribavirin.

Naveen Gara1, Marc G Ghany.   

Abstract

The treatment of chronic hepatitis C is rapidly evolving from triple therapy to regimens that do not require interferon or even ribavirin. However, pegylated interferon and ribavirin will remain the backbone of hepatitis C therapy for the time being. This review summarizes the pharmacokinetics of peginterferon and ribavirin with a particular emphasis on their side-effect profile and management. Finally, the continued role of peginterferon and ribavirin in future therapies will be discussed.

Entities:  

Keywords:  adverse events; chronic hepatitis C treatment; peginterferon; ribavirin

Mesh:

Substances:

Year:  2013        PMID: 23429551      PMCID: PMC3641865          DOI: 10.1093/cid/cit074

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN: 1058-4838            Impact factor:   9.079


  46 in total

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7.  Adherence and mental side effects during hepatitis C treatment with interferon alfa and ribavirin in psychiatric risk groups.

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Authors:  Mark S Sulkowski; Fred Poordad; Michael P Manns; Jean-Pierre Bronowicki; K Rajender Reddy; Stephen A Harrison; Nezam H Afdhal; Heather L Sings; Lisa D Pedicone; Kenneth J Koury; Vilma Sniukiene; Margaret H Burroughs; Janice K Albrecht; Clifford A Brass; Ira M Jacobson
Journal:  Hepatology       Date:  2013-02-11       Impact factor: 17.425

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