Literature DB >> 234291

Immunotherapy of melanoma with BCG: two fatalities following intralesional injection.

C F McKhann, C G Hendrickson, L E Spitler, A Gunnarsson, D Banerjee, W R Nelson.   

Abstract

Two fatalities are reported following intralesional injection of BCG for immunotherapy of malignant melanoma. In both cases the terminal events were characterized by high fevers, major clotting defects, hypotension, and anuria, suggesting that the mechanism was hypersensitivity to BCG.

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Year:  1975        PMID: 234291     DOI: 10.1002/1097-0142(197502)35:2<514::aid-cncr2820350233>3.0.co;2-f

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  12 in total

Review 1.  Intralesional Immunotherapy for Metastatic Melanoma: The Oldest and Newest Treatment in Oncology.

Authors:  Mark B Faries
Journal:  Crit Rev Oncog       Date:  2016

2.  Pulmonary tuberculosis due to bacille Calmette-Guérin.

Authors:  D Kirsten; U Rieger; K H Schröder; A Böhle; H Magnussen
Journal:  Clin Investig       Date:  1993-10

3.  Immunotherapy as an adjunct to surgery in the treatment of cancer.

Authors:  F R Eilber; E C Holmes; D L Morton
Journal:  World J Surg       Date:  1977-09       Impact factor: 3.352

4.  Effects of Corynebacterium parvum treatment and Toxoplasma gondii infection on macrophage-mediated cytostasis of tumour target cells.

Authors:  J L Krahenbuhl; L H Lambert; J S Remington
Journal:  Immunology       Date:  1976-12       Impact factor: 7.397

Review 5.  Melanoma vaccines: mixed past, promising future.

Authors:  Junko Ozao-Choy; Delphine J Lee; Mark B Faries
Journal:  Surg Clin North Am       Date:  2014-08-07       Impact factor: 2.741

6.  Drug therapy of bacillus Calmette-Guérin sepsis.

Authors:  S C Koukol; J I DeHaven; D R Riggs; D L Lamm
Journal:  Urol Res       Date:  1995

7.  Hypotension and disseminated intravascular coagulation following intralesional bacillus Calmette-Guérin therapy for locally metastatic melanoma.

Authors:  M H Cohen; R J Elin; B J Cohen
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

Review 8.  Modulation of the immune response by BCG: a review.

Authors:  R I Murahata; M S Mitchell
Journal:  Yale J Biol Med       Date:  1976-07

9.  Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function.

Authors:  Ricardo D Lardone; Alfred A Chan; Agnes F Lee; Leland J Foshag; Mark B Faries; Peter A Sieling; Delphine J Lee
Journal:  Front Immunol       Date:  2017-08-11       Impact factor: 7.561

10.  Intralesional injection of rose bengal induces a systemic tumor-specific immune response in murine models of melanoma and breast cancer.

Authors:  Paul Toomey; Krithika Kodumudi; Amy Weber; Lisa Kuhn; Ellen Moore; Amod A Sarnaik; Shari Pilon-Thomas
Journal:  PLoS One       Date:  2013-07-17       Impact factor: 3.240

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