R K Singh1, P K Mittal, R C Dhiman. 1. National Institute of Malaria Research (ICMR), Dwarka, New Delhi, India. singhriku@yahoo.co.in
Abstract
BACKGROUND & OBJECTIVES: Phlebotomus argentipes is the vector for visceral leishmaniasis in India. The development of resistance in kala-azar vector to DDT has been reported from various parts of India. The main objective of this study was to generate information on insecticides susceptibility status of P. argentipes to DDT, malathion and deltamethrin in different parts in three states of India. METHODS: Phlebotomus argentipes were collected from different villages, identified and used to investigate the susceptibility status against DDT, malathion and deltamethrin as per the WHO standard methods. RESULTS: Phlebotomus argentipes was resistant to DDT in different areas, viz. PHCs Murumgaon in Maharashtra; Ramgarh in Jharkhand; Kodah, Falka, Mahua and Lalganj in Bihar. In Phulwari Shareef PHC of Patna district in Bihar, DDT produced 89% mortality in P. argentipes, indicating resistant/tolerance (verification required) to DDT. The corrected percent mortality to malathion (5%) in different areas ranged between 98 and 100%; and to deltamethrin (0.05%) between 98.4 and 100%. The results showed that the tested P. argentipes are susceptible to malathion and deltamethrin. CONCLUSION: Phlebotomus argentipes are still susceptible to malathion and deltamethrin, but resistant to DDT. The susceptibility status of P. argentipes should be monitored regularly in diversified situations to ascertain the judicious use of insecticides being used for indoor residual spraying in the programme for rational use of appropriate insecticide.
BACKGROUND & OBJECTIVES:Phlebotomus argentipes is the vector for visceral leishmaniasis in India. The development of resistance in kala-azar vector to DDT has been reported from various parts of India. The main objective of this study was to generate information on insecticides susceptibility status of P. argentipes to DDT, malathion and deltamethrin in different parts in three states of India. METHODS:Phlebotomus argentipes were collected from different villages, identified and used to investigate the susceptibility status against DDT, malathion and deltamethrin as per the WHO standard methods. RESULTS:Phlebotomus argentipes was resistant to DDT in different areas, viz. PHCs Murumgaon in Maharashtra; Ramgarh in Jharkhand; Kodah, Falka, Mahua and Lalganj in Bihar. In Phulwari Shareef PHC of Patna district in Bihar, DDT produced 89% mortality in P. argentipes, indicating resistant/tolerance (verification required) to DDT. The corrected percent mortality to malathion (5%) in different areas ranged between 98 and 100%; and to deltamethrin (0.05%) between 98.4 and 100%. The results showed that the tested P. argentipes are susceptible to malathion and deltamethrin. CONCLUSION:Phlebotomus argentipes are still susceptible to malathion and deltamethrin, but resistant to DDT. The susceptibility status of P. argentipes should be monitored regularly in diversified situations to ascertain the judicious use of insecticides being used for indoor residual spraying in the programme for rational use of appropriate insecticide.
Authors: Michael Coleman; Geraldine M Foster; Rinki Deb; Rudra Pratap Singh; Hanafy M Ismail; Pushkar Shivam; Ayan Kumar Ghosh; Sophie Dunkley; Vijay Kumar; Marlize Coleman; Janet Hemingway; Mark J I Paine; Pradeep Das Journal: Proc Natl Acad Sci U S A Date: 2015-06-29 Impact factor: 11.205
Authors: David S Denlinger; Joseph A Creswell; J Laine Anderson; Conor K Reese; Scott A Bernhardt Journal: Parasit Vectors Date: 2016-04-15 Impact factor: 3.876
Authors: Geraldine M Foster; Sophie Dunkley; Rinki M Deb; Edward Thomsen; Marlize Coleman; A C Dhariwal; R K Das Gupta; Sridhar Srikantiah; Pradeep Das; Michael Coleman Journal: Int Health Date: 2017-05-01 Impact factor: 2.473