Literature DB >> 23428328

Mechanotransduction: vinculin provides stability when tension rises.

Emma Spanjaard1, Johan de Rooij.   

Abstract

By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID： 23428328     DOI： 10.1016/j.cub.2013.01.020

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  10 in total

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  10 in total

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