Literature DB >> 23425864

Venous thromboembolism in psychogeriatric in-patients--a study of risk assessment, incidence, and current prophylaxis prescribing.

Xinsheng Liu1, Fintan O'Rourke, Huong Van Nguyen.   

Abstract

BACKGROUND: While venous thromboembolism (VTE) risk assessment and prophylaxis is well established for medical and surgical in-patients, there is a paucity of evidence, and therefore guidelines, in this area for psychogeriatric in-patients. We wished to determine VTE incidence, risk, and use of prophylaxis, in a psychogeriatric in-patient population.
METHODS: Retrospective audit of consecutive psychogeriatric patients aged 65 years and over admitted to Bankstown Hospital over a 3-year period, 2007-2009. Using an adapted VTE risk scoring system, patients were assigned as low, medium, or high VTE risk.
RESULTS: A total of 192 patients were included in the study. Mean age was 79.1 ± 7.0 years. Out of the total, 55.2% of patients had diagnosis of dementia, and 33.3% had depression. Overall, 81.8% (157/192) were assessed as low risk, and 18.2% (35/192) as medium risk. Also, 16.7% (32/192) received VTE prophylaxis. Four new VTE events occurred in medium-risk group, and one in low-risk group (p = 0.004). Overall VTE incidence was 10.5/10,000 patient-days, but 44.2 per 10,000 in medium-risk group. VTE risk score was predictive of VTE events - IRR 6.02 (95% Confidence Intervals (CI) = 1.76-20.7, p = 0.004) for every one-point increment in risk. Depression was associated with significantly higher VTE occurrence (6.3% in those with diagnosis vs. 0.8% without, p = 0.043).
CONCLUSION: Using a VTE risk scoring system adapted for psychogeriatric in-patients, those assessed to be at medium risk had a significantly increased rate of VTE. On this basis, we would recommend VTE prophylaxis be prescribed for psychogeriatric in-patients assessed to be at medium and high level of risk.

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Year:  2013        PMID: 23425864     DOI: 10.1017/S1041610212002268

Source DB:  PubMed          Journal:  Int Psychogeriatr        ISSN: 1041-6102            Impact factor:   3.878


  3 in total

1.  Depressive symptoms as a novel risk factor for recurrent venous thromboembolism: a longitudinal observational study in patients referred for thrombophilia investigation.

Authors:  Roland von Känel; Angelina Margani; Stefanie Stauber; Fiorenza A Meyer; Franziska Demarmels Biasiutti; Franziska Vökt; Thomas Wissmann; Bernhard Lämmle; Paul S Lukas
Journal:  PLoS One       Date:  2015-05-04       Impact factor: 3.240

Review 2.  Venous Thromboembolism During Treatment with Antipsychotics: A Review of Current Evidence.

Authors:  Anna K Jönsson; Johan Schill; Hans Olsson; Olav Spigset; Staffan Hägg
Journal:  CNS Drugs       Date:  2018-01       Impact factor: 5.749

3.  Assessment of venous thromboembolism risk and initiation of appropriate prophylaxis in psychiatric patients.

Authors:  Ann Marie Ruhe; Amy Hebbard; Genevieve Hayes
Journal:  Ment Health Clin       Date:  2018-03-26
  3 in total

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