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Literature DB >> 23424347

Ultrasensitive measurement of protein and nucleic Acid biomarkers for earlier disease detection and more effective therapies.

Abstract

Clinical decision making stands to benefit from ultrasensitive molecular diagnostic tools that identify disease-related changes in biomarker levels before advanced clinical signs and symptoms manifest.

Year: 2006 PMID： 23424347 PMCID： PMC3571029

Source DB: PubMed Journal: Biotechnol Healthc ISSN： 1554-169X

6 in total

1. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.

Authors: M P Lambert; A K Barlow; B A Chromy; C Edwards; R Freed; M Liosatos; T E Morgan; I Rozovsky; B Trommer; K L Viola; P Wals; C Zhang; C E Finch; G A Krafft; W L Klein
Journal: Proc Natl Acad Sci U S A Date: 1998-05-26 Impact factor: 11.205

2. Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment.

Authors: M J de Leon; S Segal; C Y Tarshish; S DeSanti; R Zinkowski; P D Mehta; A Convit; C Caraos; H Rusinek; W Tsui; L A Saint Louis; J DeBernardis; D Kerkman; F Qadri; A Gary; P Lesbre; T Wisniewski; J Poirier; P Davies
Journal: Neurosci Lett Date: 2002-11-29 Impact factor: 3.046

3. Use of proteomic patterns in serum to identify ovarian cancer.

Authors: Emanuel F Petricoin; Ali M Ardekani; Ben A Hitt; Peter J Levine; Vincent A Fusaro; Seth M Steinberg; Gordon B Mills; Charles Simone; David A Fishman; Elise C Kohn; Lance A Liotta
Journal: Lancet Date: 2002-02-16 Impact factor: 79.321

4. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease.

Authors: Dimitra G Georganopoulou; Lei Chang; Jwa-Min Nam; C Shad Thaxton; Elliott J Mufson; William L Klein; Chad A Mirkin
Journal: Proc Natl Acad Sci U S A Date: 2005-02-04 Impact factor: 11.205

Review 5. Inhibins and ovarian cancer.

Authors: David M Robertson; Enid Pruysers; Henry G Burger; Tom Jobling; Jane McNeilage; David Healy
Journal: Mol Cell Endocrinol Date: 2004-10-15 Impact factor: 4.102

6. Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study.

Authors: Harald Hampel; Katharina Buerger; Raymond Zinkowski; Stefan J Teipel; Alexander Goernitz; Niels Andreasen; Magnus Sjoegren; John DeBernardis; Daniel Kerkman; Koichi Ishiguro; Hideto Ohno; Eugeen Vanmechelen; Hugo Vanderstichele; Cheryl McCulloch; Hans-Jurgen Moller; Peter Davies; Kaj Blennow
Journal: Arch Gen Psychiatry Date: 2004-01

6 in total

Ultrasensitive measurement of protein and nucleic Acid biomarkers for earlier disease detection and more effective therapies.

1. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins.

2. Longitudinal cerebrospinal fluid tau load increases in mild cognitive impairment.

3. Use of proteomic patterns in serum to identify ovarian cancer.

4. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease.

Review 5. Inhibins and ovarian cancer.

6. Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study.

1. Fluorescent carbon nanoparticle-based lateral flow biosensor for ultrasensitive detection of DNA.

2. Universal Biotin-PEG-Linked Gold Nanoparticle Probes for the Simultaneous Detection of Nucleic Acids and Proteins.

Review 3. Salivary diagnostics using a portable point-of-service platform: a review.

4. Pyrenyl carbon nanostructures for ultrasensitive measurements of formaldehyde in urine.

Review 5. Targeted delivery system of nanobiomaterials in anticancer therapy: from cells to clinics.

6. DNA-only bioassay for simultaneous detection of proteins and nucleic acids.