Literature DB >> 23423635

Imaging cancer gene activity in patients from outside the body.

Eric Wickstrom1, Mathew L Thakur.   

Abstract

Is the lump malignant or benign? The investigators propose to answer this question by injecting a nuclear medicine gene probe into patients with suspicious lumps in their breasts. They then use scanning techniques to see if active cancer genes light up.

Entities:  

Keywords:  cancer; hybridization; magnetic resonance imaging; oligonucleotides; oncogenes; positron emission tomography; scintigraphic imaging

Year:  2006        PMID： 23423635      PMCID： PMC3571036     

Source DB:  PubMed          Journal:  Biotechnol Healthc        ISSN： 1554-169X


  9 in total

1.  99mTc-labeled vasoactive intestinal peptide analog for rapid localization of tumors in humans.

Authors:  M L Thakur; C S Marcus; S Saeed; V Pallela; C Minami; L Diggles; H Le Pham; R Ahdoot; E A Kalinowski
Journal:  J Nucl Med       Date:  2000-01       Impact factor: 10.057

2.  DNA copy number changes and evaluation of MYC, IGF1R, and FES amplification in xenografts of pancreatic adenocarcinoma.

Authors:  G Armengol; S Knuutila; F Lluís; G Capellà; R Miró; M R Caballín
Journal:  Cancer Genet Cytogenet       Date:  2000-01-15

3.  Genetics and cancer.

Authors:  A G Knudson
Journal:  Postgrad Med       Date:  1970-11       Impact factor: 3.840

4.  Cancer classification with DNA microarrays is less more?

Authors:  R Wooster
Journal:  Trends Genet       Date:  2000-08       Impact factor: 11.639

5.  Noninvasive molecular imaging of MYC mRNA expression in human breast cancer xenografts with a [99mTc]peptide-peptide nucleic acid-peptide chimera.

Authors:  Xiaobing Tian; Mohan R Aruva; Wenyi Qin; Weizhu Zhu; Edward R Sauter; Mathew L Thakur; Eric Wickstrom
Journal:  Bioconjug Chem       Date:  2005 Jan-Feb       Impact factor: 4.774

Review 6.  Molecular genetic basis of pancreatic adenocarcinoma.

Authors:  W Hilgers; S E Kern
Journal:  Genes Chromosomes Cancer       Date:  1999-09       Impact factor: 5.006

7.  Synthesis of novel peptide nucleic acid-peptide chimera for non-invasive imaging of cancer.

Authors:  A Chakrabarti; M R Aruva; S P Sajankila; M L Thakur; Eric Wickstrom
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2005       Impact factor: 1.381

8.  External imaging of CCND1 cancer gene activity in experimental human breast cancer xenografts with 99mTc-peptide-peptide nucleic acid-peptide chimeras.

Authors:  Xiaobing Tian; Mohan R Aruva; Wenyi Qin; Weizhu Zhu; Kevin T Duffy; Edward R Sauter; Mathew L Thakur; Eric Wickstrom
Journal:  J Nucl Med       Date:  2004-12       Impact factor: 10.057

9.  The insulin-like growth factor I receptor: a key to tumor growth?

Authors:  R Baserga
Journal:  Cancer Res       Date:  1995-01-15       Impact factor: 12.701
  9 in total

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