| Literature DB >> 23423224 |
Zane B Starkewolf1, Larissa Miyachi, Joyce Wong, Ting Guo.
Abstract
Enhanced cellular toxicity was observed using X-ray irradiated nanoparticle drug carriers (NDC) consisting of doxorubicin (DOX) conjugated to DNA strands attached to the surface of gold nanoparticles. Kinetic studies showed that X-rays, acting as a triggering modality, generated reactive oxygen species to break DNA strands and release DOX.Entities:
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Year: 2013 PMID: 23423224 DOI: 10.1039/c3cc38100e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222