Literature DB >> 23420730

An insulinoma presenting as hypoglycaemia associated with exercise stress testing.

Fredolin Lainis1, Eoin Fahy, Matthew Murphy.   

Abstract

A 68-year-old man presented to the accident and emergency department with a history of central chest pain associated with exertion. He was admitted for assessment and when an acute coronary syndrome was excluded, he underwent exercise stress testing. His exercise stress testing was discontinued due to lightheadedness. His capillary glucose was checked and it showed hypoglycaemia (2.2 mmol/l). In light of this, a 72 h supervised fast was performed and it became positive within 24 h with low plasma glucose, inappropriately high insulin and C peptide levels. Sulfonylurea screen was negative. CT, MRI and endoscopic ultrasound revealed a 2 cm pancreatic tail insulinoma. He underwent successful surgical enucleation of this lesion.

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Year:  2013        PMID: 23420730      PMCID: PMC3603631          DOI: 10.1136/bcr-2012-008436

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  3 in total

Review 1.  Insulinomas associated with multiple endocrine neoplasia type I: the need for a different surgical approach.

Authors:  M J Demeure; D C Klonoff; J H Karam; Q Y Duh; O H Clark
Journal:  Surgery       Date:  1991-12       Impact factor: 3.982

2.  Islet cell tumors of the pancreas: clinical, radiologic, and pathologic correlation in diagnosis and localization.

Authors:  P C Buetow; D L Miller; T V Parrino; J L Buck
Journal:  Radiographics       Date:  1997 Mar-Apr       Impact factor: 5.333

3.  Localization of insulinomas to regions of the pancreas by intraarterial calcium stimulation: the NIH experience.

Authors:  Jean-Marc Guettier; Anthony Kam; Richard Chang; Monica C Skarulis; Craig Cochran; H Richard Alexander; Steven K Libutti; James F Pingpank; Phillip Gorden
Journal:  J Clin Endocrinol Metab       Date:  2009-02-03       Impact factor: 5.958

  3 in total

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