Literature DB >> 234207

Physiocochemical properties of a lipoprotein antigen of Echinococcus granulosus.

C Oriol, R Oriol.   

Abstract

Molecular weight and optical properties of the lipoprotein B, the main antigen produced by the parasite in sheep hydatid fluid, have been determined. By sedimentation equilibrium studies, its molecular weight has been found equal to 120,000. Circular dichroism and optical rotatory dispersion spectra are consistent with an alpha-helix content of about 50%, and this ordered structure is not completely destroyed by dissociation in guanidinium choloride. The ORD spectrum is discussed in relation to the biological function of the lipoprotein antigen.

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Year:  1975        PMID： 234207     DOI： 10.4269/ajtmh.1975.24.96

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  6 in total

1.  Characterization of various recombinant antigens from Echinococcus multilocularis for use in the immunodiagnosis.

Authors:  Hirokazu Kouguchi; Tomohiro Suzuki; Kimiaki Yamano; Hiroshi Honma; Yukiharu Sawada
Journal:  Protein J       Date:  2005-01       Impact factor: 2.371

2.  Immunoblotting with human native antigen shows stage-related sensitivity in the serodiagnosis of hepatic cystic echinococcosis.

Authors:  Mara Mariconti; Chiara Bazzocchi; Francesca Tamarozzi; Valeria Meroni; Francesca Genco; Roberta Maserati; Enrico Brunetti
Journal:  Am J Trop Med Hyg       Date:  2013-12-02       Impact factor: 2.345

3.  Cellular immune responses of hydatid patients to Echinococcus granulosus antigens.

Authors:  A Siracusano; A Teggi; F Quintieri; S Notargiacomo; F De Rosa; G Vicari
Journal:  Clin Exp Immunol       Date:  1988-06       Impact factor: 4.330

Review 4.  Concepts in immunology and diagnosis of hydatid disease.

Authors:  Wenbao Zhang; Jun Li; Donald P McManus
Journal:  Clin Microbiol Rev       Date:  2003-01       Impact factor: 26.132

5.  Characterisation of the native lipid moiety of Echinococcus granulosus antigen B.

Authors:  Gonzalo Obal; Ana Lía Ramos; Valeria Silva; Analía Lima; Carlos Batthyany; María Inés Bessio; Fernando Ferreira; Gustavo Salinas; Ana María Ferreira
Journal:  PLoS Negl Trop Dis       Date:  2012-05-15

6.  Lipid-free antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties.

Authors:  Valeria Silva-Álvarez; Gisela R Franchini; Jorge L Pórfido; Malcolm W Kennedy; Ana M Ferreira; Betina Córsico
Journal:  PLoS Negl Trop Dis       Date:  2015-03-13
  6 in total

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