Literature DB >> 23419371

Multiple sclerosis: preventing progression and disability in MS-when to treat?

Maura Pugliatti1.   

Abstract

In relapsing–remitting multiple sclerosis, conversion to the progressive stage is thought to be influenced by early relapses. Despite a new study suggesting that relapses do not drive long-term disability and proposing the latency period as an ideal target for therapeutic intervention, the relapsing phase remains a relevant treatment window.

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Year:  2013        PMID： 23419371     DOI： 10.1038/nrneurol.2013.28

Source DB:  PubMed          Journal:  Nat Rev Neurol        ISSN： 1759-4758            Impact factor:   42.937


  10 in total

Review 1.  Protecting axons in multiple sclerosis.

Authors:  A Wilkins; N Scolding
Journal:  Mult Scler       Date:  2008-07-16       Impact factor: 6.312

Review 2.  Accumulation of irreversible disability in multiple sclerosis: from epidemiology to treatment.

Authors:  Christian Confavreux; Sandra Vukusic
Journal:  Clin Neurol Neurosurg       Date:  2006-01-18       Impact factor: 1.876

3.  Impact of multiple sclerosis relapses on progression diminishes with time.

Authors:  H Tremlett; M Yousefi; V Devonshire; P Rieckmann; Y Zhao
Journal:  Neurology       Date:  2009-11-04       Impact factor: 9.910

Review 4.  Natural history of multiple sclerosis: long-term prognostic factors.

Authors:  Christel Renoux
Journal:  Neurol Clin       Date:  2011-05       Impact factor: 3.806

5.  Assess, compare and enhance the status of Persons with Multiple Sclerosis (MS) in Europe: a European Register for MS.

Authors:  M Pugliatti; D Eskic; T Mikolcić; D Pitschnau-Michel; K-M Myhr; J Sastre-Garriga; S Otero; L Wieczynska; C Torje; E Holloway; O Rienhoff; T Friede; K Buckow; D Ellenberger; J Hillert; A Glaser; P Flachenecker; J Fuge; T Schyns-Liharska; E Kasilingam; A Moretti; C Thalheim
Journal:  Acta Neurol Scand Suppl       Date:  2012

6.  Relapses and progression of disability in multiple sclerosis.

Authors:  C Confavreux; S Vukusic; T Moreau; P Adeleine
Journal:  N Engl J Med       Date:  2000-11-16       Impact factor: 91.245

Review 7.  Heterogeneity of multiple sclerosis pathogenesis: implications for diagnosis and therapy.

Authors:  H Lassmann; W Brück; C Lucchinetti
Journal:  Trends Mol Med       Date:  2001-03       Impact factor: 11.951

8.  Effect of relapses on development of residual deficit in multiple sclerosis.

Authors:  Fred D Lublin; Monika Baier; Gary Cutter
Journal:  Neurology       Date:  2003-12-09       Impact factor: 9.910

9.  The natural history of multiple sclerosis: a geographically based study 10: relapses and long-term disability.

Authors:  Antonio Scalfari; Anneke Neuhaus; Alexandra Degenhardt; George P Rice; Paolo A Muraro; Martin Daumer; George C Ebers
Journal:  Brain       Date:  2010-06-09       Impact factor: 13.501

10.  Early relapses, onset of progression, and late outcome in multiple sclerosis.

Authors:  Antonio Scalfari; Anneke Neuhaus; Martin Daumer; Gabriele C Deluca; Paolo A Muraro; George C Ebers
Journal:  JAMA Neurol       Date:  2013-02       Impact factor: 18.302
  10 in total

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