Literature DB >> 23418880

A new antibacterial denitroaristolochic acid from the tubers of Stephania succifera.

De-Lan Yang1, Wen-Li Mei, Yan-Bo Zeng, Zhi-Kai Guo, Dai-Jing Wei, Shou-Bai Liu, Qing-Huang Wang, Hao-Fu Dai.   

Abstract

A new denitroaristolochic acid, demethylaristofolin C (1), together with six known alkaloids, crebanine N-oxide (2), (-)-sukhodianine-β-N-oxide (3), palmatine (4), corydalmine (5), dehydrocorydalmine (6), and corynoxidine (7), was isolated from the tubers of Stephania succifera. The structure of demethylaristofolin C was elucidated by spectroscopic techniques (UV, IR, 1D, and 2D NMR) and HR-ESI-MS analyses. These compounds exhibited antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains in different degrees.

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Year:  2013        PMID: 23418880     DOI: 10.1080/10286020.2012.762641

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  2 in total

1.  Crebanine, an aporphine alkaloid, sensitizes TNF-α-induced apoptosis and suppressed invasion of human lung adenocarcinoma cells A549 by blocking NF-κB-regulated gene products.

Authors:  Supachai Yodkeeree; Wilart Pompimon; Pornngarm Limtrakul
Journal:  Tumour Biol       Date:  2014-05-28

2.  Comparative Research of Chemical Profiling in Different Parts of Fissistigma oldhamii by Ultra-High-Performance Liquid Chromatography Coupled with Hybrid Quadrupole-Orbitrap Mass Spectrometry.

Authors:  Haibo Hu; Yau Lee-Fong; Jinnian Peng; Bin Hu; Jialin Li; Yaoli Li; Hao Huang
Journal:  Molecules       Date:  2021-02-11       Impact factor: 4.411

  2 in total

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