Literature DB >> 23418264

Adherence to antihypertensive medications among family practice patients with diabetes mellitus and hypertension.

Nandini Natarajan1, Wayne Putnam, Kristine Van Aarsen, Kristine Beverley Lawson, Fred Burge.   

Abstract

OBJECTIVE: To measure adherence and to identify factors associated with adherence to antihypertensive medications in family practice patients with diabetes mellitus (DM) and hypertension.
DESIGN: A cross-sectional study using a mailed patient self-report survey and clinical data.
SETTING: Twenty-seven family physician and nurse practitioner clinics from Nova Scotia, New Brunswick, and Prince Edward Island (the Maritime Family Practice Research Network). PARTICIPANTS: A total of 527 patients with type 2 DM and hypertension who had had their blood pressure measured with the BpTRU (an automated oscillometric instrument) at family practice clinic visits within the previous 6 months. MAIN OUTCOME MEASURES: Level of adherence to antihypertension medications as measured by patients' self-report on the Morisky scale; association between high adherence on the Morisky scale and 22 patient factors related to demographic characteristics, clinical variables, knowledge, beliefs, behaviour, health care provider relationships, and health system influences.
RESULTS: The survey response rate was 89.6%. The average age of patients was 66 years, and 51.6% of participants were men. Forty-three percent of patients had had a diagnosis of DM for more than 10 years, and 49.7% had had a diagnosis of hypertension for more than 10 years. Eighty-nine percent of patients had some form of medical insurance. All patients had seen their family physician providers at least once within the past year. Seventy-seven percent of patients reported high adherence as measured by the Morisky scale. On multiple logistic regression, being older than 55, taking more than 7 prescribed medications, and having a lifestyle that included regular exercise or a healthy diet with low salt intake or both were significant independent predictors of high adherence scores on the Morisky scale (P ≤ .05).
CONCLUSION: More than three-quarters of patients with type 2 DM and hypertension from community family practice clinics in Maritime Canada reported high adherence to their antihypertensive medications. Family physicians and nurse practitioners can apply strategies to improve antihypertensive medication adherence among type 2 DM patients who are younger, taking fewer medications, or not maintaining a lifestyle that includes regular exercise or a healthy diet or both. Future studies will need to determine whether focusing adherence strategies on these patients will improve their cardiovascular outcomes.

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Year:  2013        PMID: 23418264      PMCID: PMC3576963     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN: 0008-350X            Impact factor:   3.275


  37 in total

1.  Determinants of discontinuation of new courses of antihypertensive medications.

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Journal:  J Clin Epidemiol       Date:  2002-07       Impact factor: 6.437

2.  Identifying patient and physician characteristics that affect compliance with antihypertensive medications.

Authors:  X S Ren; L E Kazis; A Lee; H Zhang; D R Miller
Journal:  J Clin Pharm Ther       Date:  2002-02       Impact factor: 2.512

Review 3.  Diabetes, hypertension, and cardiovascular disease: an update.

Authors:  J R Sowers; M Epstein; E D Frohlich
Journal:  Hypertension       Date:  2001-04       Impact factor: 10.190

4.  Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness.

Authors:  R Horne; J Weinman
Journal:  J Psychosom Res       Date:  1999-12       Impact factor: 3.006

Review 5.  Treatment and blood pressure control in 47,964 people with diabetes and hypertension: a systematic review of observational studies.

Authors:  Donna L McLean; Scot H Simpson; Finlay A McAlister; Ross T Tsuyuki
Journal:  Can J Cardiol       Date:  2006-08       Impact factor: 5.223

6.  Medication adherence and associated hemoglobin A1c in type 2 diabetes.

Authors:  Kimberley Krapek; Kathleen King; Susan S Warren; Karen G George; Dorothy A Caputo; Karen Mihelich; Elizabeth M Holst; Michael B Nichol; Sheng G Shi; Kevin B Livengood; Steve Walden; Teresa J Lubowski
Journal:  Ann Pharmacother       Date:  2004-07-06       Impact factor: 3.154

7.  Impact of a better adherence to antihypertensive agents on cerebrovascular disease for primary prevention.

Authors:  Fatima-Zohra Kettani; Alice Dragomir; Robert Côté; Louise Roy; Anick Bérard; Lucie Blais; Lyne Lalonde; Pierre Moreau; Sylvie Perreault
Journal:  Stroke       Date:  2008-11-26       Impact factor: 7.914

8.  Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients.

Authors:  Giampiero Mazzaglia; Ettore Ambrosioni; Marianna Alacqua; Alessandro Filippi; Emiliano Sessa; Vincenzo Immordino; Claudio Borghi; Ovidio Brignoli; Achille P Caputi; Claudio Cricelli; Lorenzo G Mantovani
Journal:  Circulation       Date:  2009-10-05       Impact factor: 29.690

9.  Compliance and satisfaction with raloxifene versus alendronate for the treatment of postmenopausal osteoporosis in clinical practice: An open-label, prospective, nonrandomized, observational study.

Authors:  Carmen Turbí; Gabriel Herrero-Beaumont; Juan Carlos Acebes; Antonio Torrijos; Jenaro Graña; Roberto Miguélez; JoséAntonio Sacristán; Fernando Marín
Journal:  Clin Ther       Date:  2004-02       Impact factor: 3.393

10.  Hypertension and type 2 diabetes: what family physicians can do to improve control of blood pressure--an observational study.

Authors:  Wayne Putnam; Beverley Lawson; Farokh Buhariwalla; Mary Goodfellow; Rose Anne Goodine; Jennifer Hall; Kendrick Lacey; Ian MacDonald; Frederick I Burge; Nandini Natarajan; Ingrid Sketris; Beth Mann; Peggy Dunbar; Kristine Van Aarsen; Marshall S Godwin
Journal:  BMC Fam Pract       Date:  2011-08-11       Impact factor: 2.497

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  25 in total

Review 1.  Factors associated with antihypertensive medication non-adherence: a systematic review.

Authors:  D M van der Laan; P J M Elders; C C L M Boons; J J Beckeringh; G Nijpels; J G Hugtenburg
Journal:  J Hum Hypertens       Date:  2017-06-29       Impact factor: 3.012

2.  Health Beliefs and Medication Adherence in Omanis With Hypertension.

Authors:  Huda Al-Noumani; Jia-Rong Wu; Debra Barksdale; George Knafl; Esra AlKhasawneh; Gwen Sherwood
Journal:  J Cardiovasc Nurs       Date:  2018 Nov/Dec       Impact factor: 2.083

Review 3.  Medication adherence in patients with diabetes and dyslipidemia: associated factors and strategies for improvement.

Authors:  Lucas N Marzec; Thomas M Maddox
Journal:  Curr Cardiol Rep       Date:  2013-11       Impact factor: 2.931

Review 4.  Understanding patients' adherence-related beliefs about medicines prescribed for long-term conditions: a meta-analytic review of the Necessity-Concerns Framework.

Authors:  Rob Horne; Sarah C E Chapman; Rhian Parham; Nick Freemantle; Alastair Forbes; Vanessa Cooper
Journal:  PLoS One       Date:  2013-12-02       Impact factor: 3.240

5.  Can certified health professionals treat obesity in a community-based programme? A quasi-experimental study.

Authors:  Baukje Miedema; Stacey A Reading; Ryan A Hamilton; Katherine S Morrison; Ashley E Thompson
Journal:  BMJ Open       Date:  2015-02-04       Impact factor: 2.692

6.  Adherence to pharmacotherapy and medication-related beliefs in patients with hypertension in Lima, Peru.

Authors:  Marta Fernandez-Arias; Ana Acuna-Villaorduna; J Jaime Miranda; Francisco Diez-Canseco; German Malaga
Journal:  PLoS One       Date:  2014-12-03       Impact factor: 3.240

Review 7.  Adjuvant therapy for pancreas cancer in an era of value based cancer care.

Authors:  Daniel H Ahn; Terence M Williams; Daniel A Goldstein; Bassel El-Rayes; Tanios Bekaii-Saab
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8.  Drug adherence for antihypertensive medications and its determinants among adult hypertensive patients attending in chronic clinics of referral hospitals in Northwest Ethiopia.

Authors:  Habtamu Sewunet Mekonnen; Mignote Hailu Gebrie; Kokeb Haile Eyasu; Abebaw Addis Gelagay
Journal:  BMC Pharmacol Toxicol       Date:  2017-04-05       Impact factor: 2.483

9.  Compliance with adjuvant capecitabine in patients with stage II and III colon cancer: comparison of administrative versus medical record data.

Authors:  Adam Amlani; Aalok Kumar; Jenny Y Ruan; Winson Y Cheung
Journal:  Cancer Med       Date:  2016-05-26       Impact factor: 4.452

10.  Adherence to Antihypertensives in Patients With Comorbid Condition.

Authors:  Zahra Saadat; Farahnaz Nikdoust; Hossein Aerab-Sheibani; Mostafa Bahremand; Elham Shobeiri; Habibollah Saadat; Yashar Moharramzad; Donald E Morisky
Journal:  Nephrourol Mon       Date:  2015-07-30
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