Literature DB >> 23417943

Lower limb gangrene postcardiac surgery.

Hamoun Rozati1, Sonya Pratik Shah, Ying Ying Peng.   

Abstract

A 67-year-old gentleman presented with a 1-day history of left foot pain. He had recently been discharged following a coronary artery bypass graft; during the admission, he had received an intravenous heparin infusion. Examination revealed black-purple discolouration of the first and second digits of the left foot with pitting oedema to the level of the knee. The posterior tibial and dorsalis pedis pulses were both shown to be patent. A new thrombocytopenia was noted. Ultrasound imaging revealed multiple deep vein thrombosis. The history of recent heparin exposure coupled with venous gangrene secondary to deep vein thrombosis was consistent with heparin-induced thrombocytopenia. He was treated acutely with intravenous danaparoid and later with warfarin. There was complete resolution of the venous gangrene at 1 month follow-up.

Entities:  

Mesh:

Year:  2013        PMID: 23417943      PMCID: PMC3603791          DOI: 10.1136/bcr-2012-008362

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  23 in total

1.  Evaluation of pretest clinical score (4 T's) for the diagnosis of heparin-induced thrombocytopenia in two clinical settings.

Authors:  G K Lo; D Juhl; T E Warkentin; C S Sigouin; P Eichler; A Greinacher
Journal:  J Thromb Haemost       Date:  2006-04       Impact factor: 5.824

2.  Outcomes after platelet transfusion in patients with heparin-induced thrombocytopenia.

Authors:  M A Refaai; C Chuang; M Menegus; N Blumberg; C W Francis
Journal:  J Thromb Haemost       Date:  2010-03-19       Impact factor: 5.824

3.  Guidelines on the diagnosis and management of heparin-induced thrombocytopenia: second edition.

Authors:  Henry Watson; Simon Davidson; David Keeling
Journal:  Br J Haematol       Date:  2012-10-09       Impact factor: 6.998

4.  Prevalence of heparin-associated antibodies without thrombosis in patients undergoing cardiopulmonary bypass surgery.

Authors:  T L Bauer; G Arepally; B A Konkle; B Mestichelli; S S Shapiro; D B Cines; M Poncz; S McNulty; J Amiral; W W Hauck; R N Edie; J D Mannion
Journal:  Circulation       Date:  1997-03-04       Impact factor: 29.690

5.  Overdiagnosis of heparin-induced thrombocytopenia in surgical ICU patients.

Authors:  Cherisse Berry; Oxana Tcherniantchouk; Eric J Ley; Ali Salim; James Mirocha; Sylvia Martin-Stone; Dennis Stolpner; Daniel R Margulies
Journal:  J Am Coll Surg       Date:  2011-05-04       Impact factor: 6.113

6.  Thrombocytopenia and its related factors: a hospital-based, cross-sectional study.

Authors:  Shih Wei Lai; Ching Yi Huang; Hsueh Chou Lai; Kuan Fu Liao; Yen Miao Lai; Chiu Shong Liu; Tsann Lin
Journal:  Ann Acad Med Singapore       Date:  2010-01       Impact factor: 2.473

7.  Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia.

Authors:  Maureen A Smythe; Theodore E Warkentin; Jennifer L Stephens; Dana Zakalik; Joan C Mattson
Journal:  Am J Hematol       Date:  2002-09       Impact factor: 10.047

8.  Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin.

Authors:  T E Warkentin; M N Levine; J Hirsh; P Horsewood; R S Roberts; M Gent; J G Kelton
Journal:  N Engl J Med       Date:  1995-05-18       Impact factor: 91.245

9.  Early-onset and persisting thrombocytopenia in post-cardiac surgery patients is rarely due to heparin-induced thrombocytopenia, even when antibody tests are positive.

Authors:  S Selleng; B Malowsky; U Strobel; A Wessel; T Ittermann; H-G Wollert; T E Warkentin; A Greinacher
Journal:  J Thromb Haemost       Date:  2009-09-28       Impact factor: 5.824

10.  Venous thromboembolism risk and prophylaxis in the acute hospital care setting: report from the ENDORSE study in Egypt.

Authors:  Hadi A Goubran; Sherif Sholkamy; Alaa El-Haddad; Alaa Mahmoud; Mounir A Rizkallah; George Sobhy
Journal:  Thromb J       Date:  2012-09-05
View more
  1 in total

1.  Concurrence of symmetrical peripheral gangrene and venous limb gangrene following polytrauma: a case report.

Authors:  Jih Huei Tan; Yuzaidi Mohamad; Chor Lip Henry Tan; Mahazir Kassim; Theodore E Warkentin
Journal:  J Med Case Rep       Date:  2018-05-19
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.