Literature DB >> 23417692

[Palpation and elastography of thyroid nodules in comparison].

M Etzel1, C Happel, F von Müller, H Ackermann, J Bojunga, F Grünwald.   

Abstract

UNLABELLED: In addition to ultrasound, elastography is available for evaluation of thyroid nodules for several years. AIM: of this study was to verify a statistically significant correlation between palpation and elastography as well as between scintigraphy and elastography, respectively. PATIENTS, METHODES: 97 solitary thyroid nodules in 67 women (mean age 63.0 ± 14.8 years) and 30 men (mean age 63.4 ± 18.5 years) were colour-coded by a colour spectrum from blue (soft) via yellow to red (hard) (Sonix touch ultrasound system, Ultrasonix, Canada) with a 6-14 MHz probe. These colour codes were classified into an elastography score of ES 1 to ES 4.
RESULTS: 50 nodules were not palpable, 47 were addressed as "soft" (n = 16), "indifferent" (n = 24) or "hard" (n = 7). Elastography values were higher with increasing stiffness of the palpable nodules. Medians of elastography score were for the soft nodules ES 2, for the indifferent nodules ES 2.5 and for the hard nodules ES 4. A statistically significant correlation could be confirmed by the Jonckheere-Terpstra test (p = 0.01) and Spearman's rank correlation (p = 0.03). No correlation between elastography and scintigraphic uptake could be observed (p = 0.41).
CONCLUSION: In detectable nodules, palpation is correlated with elastography. Since non-palpable nodules may have differences in elasticity too, elastography can provide additional data, which may influence the further diagnostic procedures and treatment essentially. Based on these results, scintigraphy cannot be replaced by elastography.

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Year:  2013        PMID: 23417692     DOI: 10.3413/Nukmed-0519-12-07

Source DB:  PubMed          Journal:  Nuklearmedizin        ISSN: 0029-5566            Impact factor:   1.379


  5 in total

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Journal:  Endocrine       Date:  2017-03-11       Impact factor: 3.633

2.  Focus on radioiodine-131 biokinetics: the influence of methylprednisolone on intratherapeutic effective half-life of 131I during radioiodine therapy of Graves' disease.

Authors:  C Happel; W T Kranert; D Gröner; J Baumgarten; J Halstenberg; B Bockisch; A Sabet; F Grünwald
Journal:  Endocrine       Date:  2021-01-13       Impact factor: 3.633

3.  Early assessment of high-intensity focused ultrasound treatment of benign thyroid nodules by scintigraphic means.

Authors:  Huedayi Korkusuz; Niklas Fehre; Michael Sennert; Christian Happel; Frank Grünwald
Journal:  J Ther Ultrasound       Date:  2014-09-30

4.  Volume reduction of benign thyroid nodules 3 months after a single treatment with high-intensity focused ultrasound (HIFU).

Authors:  Huedayi Korkusuz; Niklas Fehre; Michael Sennert; Christian Happel; Frank Grünwald
Journal:  J Ther Ultrasound       Date:  2015-03-04

5.  Targeted Mutational Profiling and a Powerful Risk Score as Additional Tools for the Diagnosis of Papillary Thyroid Cancer.

Authors:  Barbara Kocsis-Deák; Kristóf Árvai; Bernadett Balla; Bálint Tóbiás; Andrea Kohánka; Balázs Járay; János Horányi; János Podani; István Takács; Zsuzsanna Putz; János Kósa; Péter Lakatos
Journal:  Pathol Oncol Res       Date:  2019-11-22       Impact factor: 3.201

  5 in total

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