Literature DB >> 23417554

Asymmetric α-alkylation of aldehydes with 3-hydroxy-3-indolylox-indoles in aqueous media.

Ying Zhang1, Shun-Yi Wang, Xiao-Ping Xu, Ran Jiang, Shun-Jun Ji.   

Abstract

Organocatalyzed asymmetric α-alkylation of aldehydes with 3-hydroxy-3-indolylox-indoles in aqueous media has been developed. The reactions proceeded efficiently in the presence of the MacMillan catalyst to give the desired products in good to excellent yields with moderate diastereoselectivities and excellent enantioselectivities.

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Year:  2013        PMID: 23417554     DOI: 10.1039/c3ob00045a

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  1 in total

Review 1.  Catalytic asymmetric synthesis of biologically important 3-hydroxyoxindoles: an update.

Authors:  Bin Yu; Hui Xing; De-Quan Yu; Hong-Min Liu
Journal:  Beilstein J Org Chem       Date:  2016-05-18       Impact factor: 2.883

  1 in total

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