Literature DB >> 23417224

Head and neck reconstruction using microsurgery: a 9-year retrospective study.

G H Holom1, H Seland, E Strandenes, P G Liavaag, S Lybak, S Løes, K Tornes, H N Vintertun.   

Abstract

A total of 137 patients diagnosed with head and neck cancer underwent ablative surgery and primary free flap reconstruction during a period of 9 years, 2001-2009 (men 73.7 %, women 26.3 %). Surgery included a multidisciplinary approach involving plastic, head and neck, and maxillofacial surgeons. Squamous cell carcinoma (SCC) represented the vast majority of the diagnosed tumors (91.2 %); other tumors represented in the study were malignant melanoma, sarcoma, adenocarcinoma and blastoma. The free flaps (n = 143) used for reconstructive surgery included radial forearm flap (n = 128), fibular flap (n = 13) and rectus abdominis muscular flap (n = 2). Twenty patients (15 %) needed reoperation within 48 h due to clinical signs of hematoma (n = 8) and free flap ischemia (n = 12). Furthermore, we report a total of 12 free flap failures, giving an overall free flap success rate of 92 %. Five patients were treated due to infections at donor site (4 %). The overall survival rate (OS) in male patients diagnosed with oral SCC stage II-IV after 2 and 5 years was 82 and 78 %, respectively. Female patients in the same group displayed a 2- and 5-year OS of 78 and 67 %, respectively. Furthermore, analysis of patients treated for recurrence of primary SCC displayed a 2- and 5-year OS of 70 and 55 %, respectively. We conclude that our multidisciplinary approach and treatment algorithm for head and neck cancer including primary free flap reconstruction reconstitutes a safe and reliable tool.

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Year:  2013        PMID: 23417224     DOI: 10.1007/s00405-013-2390-7

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  34 in total

1.  Length of stay after free flap reconstruction of the head and neck.

Authors:  M W Ryan; M Hochman
Journal:  Laryngoscope       Date:  2000-02       Impact factor: 3.325

2.  Long-term results of free radial forearm flap used for oral reconstruction: functional and histological evaluation.

Authors:  Takahiko Shibahara; Ashiraf Fathy Mohammed; Akira Katakura; Takeshi Nomura
Journal:  J Oral Maxillofac Surg       Date:  2006-08       Impact factor: 1.895

3.  Improved microsurgical anastomotic patency with low molecular weight heparin.

Authors:  E F Ritter; J C Cronan; A M Rudner; D Serafin; B Klitzman
Journal:  J Reconstr Microsurg       Date:  1998-07       Impact factor: 2.873

4.  Simplifying microvascular head and neck reconstruction: a rational approach to donor site selection.

Authors:  J J Disa; A L Pusic; D H Hidalgo; P G Cordeiro
Journal:  Ann Plast Surg       Date:  2001-10       Impact factor: 1.539

Review 5.  [Should adjuvant treatments (antiplatelet agents, anticoagulants, normovolaemic haemodilution and vasodilators) be used in cervicofacial and maxillofacial free flaps reconstructive surgery?].

Authors:  D Péan; C Béliard
Journal:  Ann Fr Anesth Reanim       Date:  2004-09

6.  The radial forearm free flap for head and neck reconstruction: a review.

Authors:  G R Evans; M A Schusterman; S S Kroll; M J Miller; G P Reece; G L Robb; N Ainslie
Journal:  Am J Surg       Date:  1994-11       Impact factor: 2.565

7.  Preoperative radiochemotherapy and radical surgery in comparison with radical surgery alone. A prospective, multicentric, randomized DOSAK study of advanced squamous cell carcinoma of the oral cavity and the oropharynx (a 3-year follow-up).

Authors:  C Mohr; W Bohndorf; J Carstens; F Härle; J E Hausamen; H Hirche; H Kimmig; J Kutzner; J Mühling; J Reuther
Journal:  Int J Oral Maxillofac Surg       Date:  1994-06       Impact factor: 2.789

8.  Survival and function in patients with tumours of the head and neck operated on and reconstructed with free flaps.

Authors:  Disa Lidman; Magnus Niklasson
Journal:  Scand J Plast Reconstr Surg Hand Surg       Date:  2008

9.  Evaluation of 250 free-flap reconstructions after resection of tumours of the head and neck.

Authors:  C J O'Brien; K K Lee; H S Stern; S J Traynor; L Bron; P J Tew; K S Haghighi
Journal:  Aust N Z J Surg       Date:  1998-10

10.  Surgery and postoperative radiotherapy a valid treatment for advanced oropharyngeal carcinoma.

Authors:  Stein Lybak; Per Gunnar Liavaag; Odd R Monge; Jan Olofsson
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-08-28       Impact factor: 2.503

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  3 in total

Review 1.  Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer.

Authors:  Michele Carbone; J William Harbour; James Brugarolas; Angela Bononi; Ian Pagano; Anwesha Dey; Thomas Krausz; Harvey I Pass; Haining Yang; Giovanni Gaudino
Journal:  Cancer Discov       Date:  2020-07-20       Impact factor: 38.272

2.  Relationship between BMI and Postoperative Complications with Free Flap in Anterolateral Craniofacial Reconstruction.

Authors:  Yang Hoi Heo; Shunjiro Yagi; Kazuhiro Toriyama; Keisuke Takanari; Yasushi Fujimoto; Naoki Nishio; Masazumi Fujii; Kiyoshi Saito; Masakatsu Takahashi; Yuzuru Kamei
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-03-08

3.  Factors Influencing the Incidence of Severe Complications in Head and Neck Free Flap Reconstructions.

Authors:  Martin Broome; Naline Juilland; Yann Litzistorf; Yan Monnier; Kishore Sandu; Philippe Pasche; Peter K Plinkert; Philippe A Federspil; Christian Simon
Journal:  Plast Reconstr Surg Glob Open       Date:  2016-10-27
  3 in total

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