Literature DB >> 23412753

N, N, N', N'-Tetrabromobenzene-1,3-disulfonamide and poly (N-bromo-N-ethylbenzene-1,3-disulfonamide) as new and efficient catalysts for the synthesis of highly substituted 1,6-dihydropyrazine-2,3-dicarbonitrile derivatives.

Ramin Ghorbani-Vaghei1, Mostafa Amiri, Rahman Karimi-Nami, Zahra Toghraei-Semiromi, Mehdi Ghavidel.   

Abstract

Various mono and bis-1,6-dihydropyrazine-2,3-dicarbonitrile derivatives were efficiently synthesized by reacting 2,3-diaminomaleonitrile (DAMN), isocyanides and ketones in the presence of a catalytic amount of N, N, N ,N-tetrabromobenzene-1,3-disulfonamide [TBBDA] and poly(N-bromo-N-ethylbenzene-1,3-disulfonamide) [PBBS] in EtOH/H2O at ambient temperature.

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Year:  2013        PMID： 23412753     DOI： 10.1007/s11030-013-9427-0

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  13 in total

1.  Structure revision of the antibiotic echinomycin.

Authors:  A Dell; D H Williams; H R Morris; G A Smith; J Feeney; G C Roberts
Journal:  J Am Chem Soc       Date:  1975-04-30       Impact factor: 15.419

2.  Multicomponent Reactions with Isocyanides.

Authors: 
Journal:  Angew Chem Int Ed Engl       Date:  2000-09-15       Impact factor: 15.336

3.  Organic reactions in aqueous media with a focus on carbon-carbon bond formations: a decade update.

Authors:  Chao-Jun Li
Journal:  Chem Rev       Date:  2005-08       Impact factor: 60.622

4.  Straightforward access to pyrazines, piperazinones, and quinoxalines by reactions of 1,2-diaza-1,3-butadienes with 1,2-diamines under solution, solvent-free, or solid-phase conditions.

Authors:  Domitila Aparicio; Orazio A Attanasi; Paolino Filippone; Roberto Ignacio; Samuele Lillini; Fabio Mantellini; Francisco Palacios; Jesús M de Los Santos
Journal:  J Org Chem       Date:  2006-08-04       Impact factor: 4.354

5.  Recognition elements that determine affinity and sequence-specific binding to DNA of 2QN, a biosynthetic bis-quinoline analogue of echinomycin.

Authors:  C Bailly; S Echepare; F Gago; M J Waring
Journal:  Anticancer Drug Des       Date:  1999-06

6.  Novel 5,7-disubstituted 6-amino-5H-pyrrolo[3,2-b]pyrazine-2,3-dicarbonitriles, the promising protein kinase inhibitors with antiproliferative activity.

Authors:  G G Dubinina; M O Platonov; S M Golovach; P O Borysko; A O Tolmachov; Y M Volovenko
Journal:  Eur J Med Chem       Date:  2006-05-03       Impact factor: 6.514

7.  Effects of phenyl derivatives of dihydropyrazines with ability to generate radical species on Escherichia coli.

Authors:  Osamu Takeda; Shinji Takechi; Shigeru Ito; Hisamitsu Omori; Takahiko Katoh; Tadatoshi Yamaguchi
Journal:  Biol Pharm Bull       Date:  2007-09       Impact factor: 2.233

8.  A practical and efficient synthesis of bis(indolyl)methanes in water, and synthesis of di-, tri-, and tetra(bis-indolyl)methanes under thermal conditions catalyzed by oxalic acid dihydrate.

Authors:  Ramin Ghorbani-Vaghei; Hojat Veisi; Hassan Keypour; Ahmad Ali Dehghani-Firouzabadi
Journal:  Mol Divers       Date:  2009-05-16       Impact factor: 2.943

9.  Imidazo[1,2-a]quinoxalines accessed via two sequential isocyanide-based multicomponent reactions.

Authors:  Mikhail Krasavin; Sergey Shkavrov; Vladislav Parchinsky; Konstantin Bukhryakov
Journal:  J Org Chem       Date:  2009-03-20       Impact factor: 4.354

10.  Synthesis and biological evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors.

Authors:  Sunil K Singh; V Saibaba; V Ravikumar; Santosh V Rudrawar; Pankaj Daga; C Seshagiri Rao; V Akhila; P Hegde; Y Koteswar Rao
Journal:  Bioorg Med Chem       Date:  2004-04-15       Impact factor: 3.641
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