Literature DB >> 23412204

Successful treatment of congenital pseudarthrosis of the tibia: still a challenge.

K Bobotas1, S N Lallos, V S Nikolaou, D S Kοrres, N E Efstathopoulos.   

Abstract

The congenital pseudarthrosis of the tibia (CPT) is one of the most challenging problems in pediatric orthopedics. The primary treatment goals are outlined as osteosynthesis, stabilization of the ankle mortise by fibular stabilization and lower-limb-length equalization. Despite the fact that each of the aforementioned goals is difficult to be achieved regardless the surgical option, the main biological consideration is the same: pseudarthrosis resection, biological bone bridging of the defect by stable fixation and the correction of any angular deformity. The external fixation method is suggested as valuable treatment of CPT because it can address not only pseudarthrosis but also all complex deformities associated with this condition. However, treatment of CPT is impaired with complications due to the complex nature of the disease thus failure is common. The most common of these are refracture, growth disturbance, poor foot and ankle function with stiffness. Of these, refracture is the most common and serious complication after primary healing and might result in the reestablishment of pseudarthrosis. Therefore, an effective, safe and practical treatment method that minimizes the residual challenges after healing and accomplishes the multiple goals of treatment is needed. In this article, we report a patient with CPT treated successfully with external fixation. Level of evidence IV retrospective.

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Year:  2012        PMID: 23412204     DOI: 10.1007/s00590-012-1072-2

Source DB:  PubMed          Journal:  Eur J Orthop Surg Traumatol        ISSN: 1633-8065


  54 in total

1.  Abnormal development of the lesser wing of the sphenoid with microphthalmos and microcephaly.

Authors:  C Jacquemin; P Mullaney; T M Bosley
Journal:  Neuroradiology       Date:  2001-02       Impact factor: 2.804

2.  Intramedullary fixation and bone grafting for congenital pseudarthrosis of the tibia.

Authors:  Hyun Woo Kim; Stuart L Weinstein
Journal:  Clin Orthop Relat Res       Date:  2002-12       Impact factor: 4.176

Review 3.  Congenital pseudarthrosis of the tibia.

Authors:  S Pannier
Journal:  Orthop Traumatol Surg Res       Date:  2011-10-12       Impact factor: 2.256

4.  Treatment of congenital pseudarthrosis of the tibia: a multicenter study in Japan.

Authors:  Isao Ohnishi; Wakyo Sato; Juntarou Matsuyama; Hiroshi Yajima; Nobuhiko Haga; Makoto Kamegaya; Akio Minami; Masato Sato; Shinji Yoshino; Takashi Oki; Kozo Nakamura
Journal:  J Pediatr Orthop       Date:  2005 Mar-Apr       Impact factor: 2.324

5.  Ilizarov technique in the treatment of congenital pseudarthrosis of the tibia.

Authors:  I Ghanem; J P Damsin; H Carlioz
Journal:  J Pediatr Orthop       Date:  1997 Sep-Oct       Impact factor: 2.324

6.  Radiological classification of congenital pseudarthrosis of the tibia.

Authors:  K S Andersen
Journal:  Acta Orthop Scand       Date:  1973

7.  Double inactivation of NF1 in tibial pseudarthrosis.

Authors:  David A Stevenson; Holly Zhou; Shadi Ashrafi; Ludwine M Messiaen; John C Carey; Jacques L D'Astous; Stephen D Santora; David H Viskochil
Journal:  Am J Hum Genet       Date:  2006-05-10       Impact factor: 11.025

8.  [Ilizarov's transosseous osteosynthesis in treating congenital pseudoarthroses of the leg].

Authors:  V I Gracheva; V D Makushin; V I Shevtsov; L M Kuftyrev; V E Degtiarev
Journal:  Ortop Travmatol Protez       Date:  1981-07

9.  Bone mineral density in children and adolescents with neurofibromatosis type 1.

Authors:  David A Stevenson; Laurie J Moyer-Mileur; Mary Murray; Hillarie Slater; Xiaoming Sheng; John C Carey; Bukhosi Dube; David H Viskochil
Journal:  J Pediatr       Date:  2007-01       Impact factor: 4.406

Review 10.  Congenital pseudarthrosis of the tibia.

Authors:  A D Delgado-Martínez; E C Rodríguez-Merchán; B Olsen
Journal:  Int Orthop       Date:  1996       Impact factor: 3.075

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