BACKGROUND: To study the expression levels and clinical significance of Argonaute2 (EIF2C2) on colonic carcinomas and normal tissues. METHODS: Colon tissue samples from 90 cases of colonic carcinomas and 90 normal subjects were accumulated and made into a tissue microarray containing 360 dots. Expression of Argonaute2 (EIF2C2) was detected by immunohistochemical staining of the tissue microarray. RESULTS: There was significant difference in the expression levels of Argonaute2 (EIF2C2) between colonic carcinomas and normal tissues (P<0.01). However, the expression of Argonaute2 (EIF2C2) was not related to sex, age, position, differentiation, lymphatic metastasis and clinical stage of the tumor (P>0.05). CONCLUSION: Abnormal expression of Argonaute2 (EIF2C2) may be correlated with colon tumorigenesis.
BACKGROUND: To study the expression levels and clinical significance of Argonaute2 (EIF2C2) on colonic carcinomas and normal tissues. METHODS: Colon tissue samples from 90 cases of colonic carcinomas and 90 normal subjects were accumulated and made into a tissue microarray containing 360 dots. Expression of Argonaute2 (EIF2C2) was detected by immunohistochemical staining of the tissue microarray. RESULTS: There was significant difference in the expression levels of Argonaute2 (EIF2C2) between colonic carcinomas and normal tissues (P<0.01). However, the expression of Argonaute2 (EIF2C2) was not related to sex, age, position, differentiation, lymphatic metastasis and clinical stage of the tumor (P>0.05). CONCLUSION: Abnormal expression of Argonaute2 (EIF2C2) may be correlated with colon tumorigenesis.
Authors: Simion Chiosea; Elena Jelezcova; Uma Chandran; Jianhua Luo; Geeta Mantha; Robert W Sobol; Sanja Dacic Journal: Cancer Res Date: 2007-03-01 Impact factor: 12.701
Authors: Simion Chiosea; Elena Jelezcova; Uma Chandran; Marie Acquafondata; Teresa McHale; Robert W Sobol; Rajiv Dhir Journal: Am J Pathol Date: 2006-11 Impact factor: 4.307
Authors: B Muralidhar; L D Goldstein; G Ng; D M Winder; R D Palmer; E L Gooding; N L Barbosa-Morais; G Mukherjee; N P Thorne; I Roberts; M R Pett; N Coleman Journal: J Pathol Date: 2007-08 Impact factor: 7.996
Authors: Petra Vychytilova-Faltejskova; Alena Svobodova Kovarikova; Tomas Grolich; Vladimir Prochazka; Katerina Slaba; Tana Machackova; Jana Halamkova; Marek Svoboda; Zdenek Kala; Igor Kiss; Ondrej Slaby Journal: Int J Mol Sci Date: 2019-09-10 Impact factor: 5.923