| Literature DB >> 2341021 |
J S Serrano1, M I Serrano, M R Guerrero, R Ruiz, J Polo.
Abstract
1. We have tested the effect of taurine on nociceptive stimulation provoked by chemical agent (acetic acid) and by the hot-plate test. 2. In the acetic acid test, taurine exerts an antinociceptive effect at every dose and time assayed. The observed effect was dose-related. 3. Naxolone pretreatment antagonizes the antinociceptive effect of taurine in the acetic acid test. 4. The results obtained in hot-plate test show that taurine did not significantly affect latency time for paw licking.Entities:
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Year: 1990 PMID： 2341021 DOI： 10.1016/0306-3623(90)90833-8
Source DB: PubMed Journal: Gen Pharmacol ISSN： 0306-3623