| Literature DB >> 2340757 |
J Meyne1, R J Baker, H H Hobart, T C Hsu, O A Ryder, O G Ward, J E Wiley, D H Wurster-Hill, T L Yates, R K Moyzis.
Abstract
The intrachromosomal distribution of non-telomeric sites of the (TTAGGG)n telomeric repeat was determined for 100 vertebrate species. The most common non-telomeric location of this sequence was in the pericentric regions of chromosomes. A variety of species showed relatively large amounts of this sequence present within regions of constitutive heterochromatin. We discuss possible relationships between the non-telomeric distribution of the (TTAGGG)n sequence and the process of karyotype evolution, during which these sites may provide potential new telomeres.Mesh:
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Year: 1990 PMID: 2340757 DOI: 10.1007/bf01737283
Source DB: PubMed Journal: Chromosoma ISSN: 0009-5915 Impact factor: 4.316