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Literature DB >> 23407051

Valproic acid pathway: pharmacokinetics and pharmacodynamics.

Yogita Ghodke-Puranik¹, Caroline F Thorn, Jatinder K Lamba, J Steven Leeder, Wen Song, Angela K Birnbaum, Russ B Altman, Teri E Klein.

Abstract

Entities: Chemical Disease Gene Mutation Species

Mesh：

Substances：

Year: 2013 PMID： 23407051 PMCID： PMC3696515 DOI： 10.1097/FPC.0b013e32835ea0b2

Source DB: PubMed Journal: Pharmacogenet Genomics ISSN： 1744-6872 Impact factor: 2.089

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38 in total

Review 1. Metabolic activation of valproic acid and drug-mediated hepatotoxicity. Role of the terminal olefin, 2-n-propyl-4-pentenoic acid.

Authors: T A Baillie
Journal: Chem Res Toxicol Date: 1988 Jul-Aug Impact factor: 3.739

2. Identification and characterization of the glutathione and N-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans.

Authors: K Kassahun; K Farrell; F Abbott
Journal: Drug Metab Dispos Date: 1991 Mar-Apr Impact factor: 3.922

3. Association of genetic variants in six candidate genes with valproic acid therapy optimization.

Authors: Chin-Chuan Hung; Jia-Ling Ho; Wei-Lun Chang; John Jen Tai; Tsung-Jen Hsieh; Yow-Wen Hsieh; Horng-Huei Liou
Journal: Pharmacogenomics Date: 2011-08-01 Impact factor: 2.533

4. Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes.

Authors: P C Ho; F S Abbott; U M Zanger; T K H Chang
Journal: Pharmacogenomics J Date: 2003 Impact factor: 3.550

5. Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status.

Authors: W Tang; A G Borel; T Fujimiya; F S Abbott
Journal: Chem Res Toxicol Date: 1995 Jul-Aug Impact factor: 3.739

6. Metabolic activation of unsaturated derivatives of valproic acid. Identification of novel glutathione adducts formed through coenzyme A-dependent and -independent processes.

Authors: K Kassahun; P Hu; M P Grillo; M R Davis; L Jin; T A Baillie
Journal: Chem Biol Interact Date: 1994-03 Impact factor: 5.192

7. Valproate and sodium currents in cultured hippocampal neurons.

Authors: R J Van den Berg; P Kok; R A Voskuyl
Journal: Exp Brain Res Date: 1993 Impact factor: 1.972

8. Relationship between carbamoyl-phosphate synthetase genotype and systemic vascular function.

Authors: Marshall L Summar; James V Gainer; Mias Pretorius; Hector Malave; Stephanie Harris; Lynn D Hall; Alec Weisberg; Douglas E Vaughan; Brian W Christman; Nancy J Brown
Journal: Hypertension Date: 2004-01-12 Impact factor: 10.190

9. Studies on the biotransformation in the perfused rat liver of 2-n-propyl-4-pentenoic acid, a metabolite of the antiepileptic drug valproic acid. Evidence for the formation of chemically reactive intermediates.

Authors: A W Rettenmeier; K S Prickett; W P Gordon; S M Bjorge; S L Chang; R H Levy; T A Baillie
Journal: Drug Metab Dispos Date: 1985 Jan-Feb Impact factor: 3.922

10. In vivo formation of the thiol conjugates of reactive metabolites of 4-ene VPA and its analog 4-pentenoic acid.

Authors: K Kassahun; F Abbott
Journal: Drug Metab Dispos Date: 1993 Nov-Dec Impact factor: 3.922

88 in total

1. Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data.

Authors: R L Smith; T Haslemo; H Refsum; E Molden
Journal: Eur J Clin Pharmacol Date: 2016-06-29 Impact factor: 2.953

2. Novel Mechanisms of Valproate Hepatotoxicity: Impaired Mrp2 Trafficking and Hepatocyte Depolarization.

Authors: Dong Fu; Panli Cardona; Henry Ho; Paul B Watkins; Kim L R Brouwer
Journal: Toxicol Sci Date: 2019-07-31 Impact factor: 4.849

3. Interaction between ABCG2 421C>A polymorphism and valproate in their effects on steady-state disposition of lamotrigine in adults with epilepsy.

Authors: Iva Klarica Domjanović; Mila Lovrić; Vladimir Trkulja; Željka Petelin-Gadže; Lana Ganoci; Ivana Čajić; Nada Božina
Journal: Br J Clin Pharmacol Date: 2018-07-08 Impact factor: 4.335

Review 4. Valproic acid-induced hyperammonemic encephalopathy in a full-term neonate: a brief review and case report.

Authors: Pavla Pokorná; Karolina Hronová; Martin Šíma; Ondřej Slanař; Petr Klement; John N van den Anker; Dick Tibboel
Journal: Eur J Clin Pharmacol Date: 2017-02-06 Impact factor: 2.953

Review 5. Environmental, genetic and epigenetic contributions to cocaine addiction.

Authors: R Christopher Pierce; Bruno Fant; Sarah E Swinford-Jackson; Elizabeth A Heller; Wade H Berrettini; Mathieu E Wimmer
Journal: Neuropsychopharmacology Date: 2018-02-05 Impact factor: 7.853

6. Postnatal treatment using curcumin supplements to amend the damage in VPA-induced rodent models of autism.

Authors: Maha Al-Askar; Ramesa Shafi Bhat; Manar Selim; Laila Al-Ayadhi; Afaf El-Ansary
Journal: BMC Complement Altern Med Date: 2017-05-10 Impact factor: 3.659

7. Enhancing Completion of Cognitive Processing Therapy for Posttraumatic Stress Disorder with Quetiapine in Veterans with Mild Traumatic Brain Injury: a Case Series.

Authors: Muhammad R Baig; Jennifer L Wilson; Jennifer A Lemmer; Robert D Beck; Alan L Peterson; John D Roache
Journal: Psychiatr Q Date: 2019-06