| Literature DB >> 23403861 |
Benjamin Terrier1, Dominique Costagliola, Sophie Prevot, Houria Chavez, Pascale Missy, Patricia Rince, Regis Costello, Lelia Escaut, Jean Gabarre, Bertrand Joly, Lorraine Letranchant, Steven Le Gouill, Pascale Morineau-Le Houssine, Anne Simon, Danielle Canioni, Olivier Hermine, Patrice Cacoub, Yassine Taoufik, Martine Raphael, Caroline Besson.
Abstract
Hepatitis C virus (HCV) infection is frequent among HIV-infected patients. We describe, the characteristics of 6 HIV/HCV-coinfected patients with B-cell non-Hodgkin lymphoma (NHL) included in a prospective cohort study of HIV-related lymphomas. Five of the 6 cases had features of marginal zone/lymphoplasmacytic NHL versus 1 of 33 HIV only-infected patients. Remarkably, anti-HCV treatment led to a hematological response in a patient with splenic marginal zone lymphoma. This supports the role of chronic antigenic stimulation by HCV on lymphomagenesis and further evaluation of HCV antiviral therapy in coinfected patients with NHL.Entities:
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Year: 2013 PMID: 23403861 DOI: 10.1097/QAI.0b013e31828a77f0
Source DB: PubMed Journal: J Acquir Immune Defic Syndr ISSN: 1525-4135 Impact factor: 3.731