Literature DB >> 23402333

Intrapatient emergence of OXA-247: a novel carbapenemase found in a patient previously infected with OXA-163-producing Klebsiella pneumoniae.

S Gomez1, F Pasteran, D Faccone, M Bettiol, O Veliz, D De Belder, M Rapoport, B Gatti, A Petroni, A Corso.   

Abstract

Two genetically related Klebsiella pneumoniae strains carrying OXA-type carbapenemases were isolated from a single patient 1 month apart. Kpn163 harboured OXA-163 and Kpn247 a new variant named OXA-247 that showed susceptibility to carbapenems and expanded-spectrum cephalosporins similar to OXA-48. Our epidemiological, biochemical and molecular results suggest the intrapatient emergence of blaOXA -247 from blaOXA -163.
© 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

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Year:  2013        PMID： 23402333     DOI： 10.1111/1469-0691.12142

Source DB:  PubMed          Journal:  Clin Microbiol Infect        ISSN： 1198-743X            Impact factor:   8.067


  25 in total

1.  Structural Basis for Different Substrate Profiles of Two Closely Related Class D β-Lactamases and Their Inhibition by Halogens.

Authors:  Vlatko Stojanoski; Dar-Chone Chow; Bartlomiej Fryszczyn; Liya Hu; Patrice Nordmann; Laurent Poirel; Banumathi Sankaran; B V Venkataram Prasad; Timothy Palzkill
Journal:  Biochemistry       Date:  2015-05-14       Impact factor: 3.162

2.  Genetic and biochemical characterization of OXA-405, an OXA-48-type extended-spectrum β-lactamase without significant carbapenemase activity.

Authors:  Laurent Dortet; Saoussen Oueslati; Katy Jeannot; Didier Tandé; Thierry Naas; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2015-04-13       Impact factor: 5.191

3.  Evaluation of the Blue-Carba test for rapid detection of carbapenemases in gram-negative bacilli.

Authors:  Fernando Pasteran; Omar Veliz; Paola Ceriana; Celeste Lucero; Melina Rapoport; Ezequiel Albornoz; Sonia Gomez; Alejandra Corso
Journal:  J Clin Microbiol       Date:  2015-03-25       Impact factor: 5.948

4.  Detection of OXA-370, an OXA-48-related class D β-lactamase, in Enterobacter hormaechei from Brazil.

Authors:  Jorge L M Sampaio; Vanessa B Ribeiro; Juliana Coutinho Campos; Franciéli P Rozales; Cibele M Magagnin; Diego R Falci; Renato Cassol F da Silva; Micheline G Dalarosa; Daniela I Luz; Fabiane J Vieira; Laura C Antochevis; Afonso Luis Barth; Alexandre P Zavascki
Journal:  Antimicrob Agents Chemother       Date:  2014-04-07       Impact factor: 5.191

5.  Rapid Identification of OXA-48 and OXA-163 Subfamilies in Carbapenem-Resistant Gram-Negative Bacilli with a Novel Immunochromatographic Lateral Flow Assay.

Authors:  Fernando Pasteran; Laurence Denorme; Isabelle Ote; Sonia Gomez; Denise De Belder; Youri Glupczynski; Pierre Bogaerts; Barbara Ghiglione; Pablo Power; Pascal Mertens; Alejandra Corso
Journal:  J Clin Microbiol       Date:  2016-08-17       Impact factor: 5.948

6.  Role of Arginine 214 in the Substrate Specificity of OXA-48.

Authors:  Saoussen Oueslati; Pascal Retailleau; Ludovic Marchini; Camille Berthault; Laurent Dortet; Rémy A Bonnin; Bogdan I Iorga; Thierry Naas
Journal:  Antimicrob Agents Chemother       Date:  2020-04-21       Impact factor: 5.191

Review 7.  The Global Ascendency of OXA-48-Type Carbapenemases.

Authors:  Johann D D Pitout; Gisele Peirano; Marleen M Kock; Kathy-Anne Strydom; Yasufumi Matsumura
Journal:  Clin Microbiol Rev       Date:  2019-11-13       Impact factor: 26.132

8.  Dissemination and Characteristics of a Novel Plasmid-Encoded Carbapenem-Hydrolyzing Class D β-Lactamase, OXA-436, Found in Isolates from Four Patients at Six Different Hospitals in Denmark.

Authors:  Ørjan Samuelsen; Frank Hansen; Bettina Aasnæs; Henrik Hasman; Bjarte Aarmo Lund; Hanna-Kirsti S Leiros; Berit Lilje; Jessin Janice; Lotte Jakobsen; Pia Littauer; Lillian M Søes; Barbara J Holzknecht; Leif P Andersen; Marc Stegger; Paal S Andersen; Anette M Hammerum
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

9.  Dissemination of bla OXA-370 gene among several Enterobacteriaceae species in Brazil.

Authors:  C M Magagnin; F P Rozales; L Antochevis; L S Nunes; A S Martins; A L Barth; J M Sampaio; A P Zavascki
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-05-30       Impact factor: 3.267

Review 10.  OXA-48-like carbapenemases producing Enterobacteriaceae in different niches.

Authors:  Assia Mairi; Alix Pantel; Albert Sotto; Jean-Philippe Lavigne; Aziz Touati
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2017-10-08       Impact factor: 3.267
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