Literature DB >> 23402028

Complement-targeted therapeutics in periodontitis.

George Hajishengallis1, John D Lambris.   

Abstract

Periodontitis is a prevalent oral chronic inflammatory disease which, in severe forms, may exert a major impact on systemic health. Clinical and histological observations, as well as experimental animal studies, suggest involvement of the complement system in periodontitis. However, the precise roles of the various complement components and pathways in periodontitis have only recently started to be elucidated. In this chapter, we review recent progress in the field and discuss the potential of complement-targeted therapeutics in the treatment of periodontitis.

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Year:  2013        PMID： 23402028      PMCID： PMC3466049          DOI： 10.1007/978-1-4614-4118-2_13

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  72 in total

Review 1.  Complex species interactions and the dynamics of ecological systems: long-term experiments.

Authors:  J H Brown; T G Whitham; S K Morgan Ernest; C A Gehring
Journal:  Science       Date:  2001-07-27       Impact factor: 47.728

2.  A critical role for C5L2 in the pathogenesis of experimental allergic asthma.

Authors:  Xun Zhang; Inken Schmudde; Yves Laumonnier; Manoj K Pandey; Jennifer R Clark; Peter König; Norma P Gerard; Craig Gerard; Marsha Wills-Karp; Jörg Köhl
Journal:  J Immunol       Date:  2010-10-25       Impact factor: 5.422

Review 3.  Complement and its role in innate and adaptive immune responses.

Authors:  Jason R Dunkelberger; Wen-Chao Song
Journal:  Cell Res       Date:  2009-12-15       Impact factor: 25.617

Review 4.  Periodontal diseases.

Authors:  Bruce L Pihlstrom; Bryan S Michalowicz; Newell W Johnson
Journal:  Lancet       Date:  2005-11-19       Impact factor: 79.321

Review 5.  The gingival tissues: the architecture of periodontal protection.

Authors:  H E Schroeder; M A Listgarten
Journal:  Periodontol 2000       Date:  1997-02       Impact factor: 7.589

6.  Microbial hijacking of complement-toll-like receptor crosstalk.

Authors:  Min Wang; Jennifer L Krauss; Hisanori Domon; Kavita B Hosur; Shuang Liang; Paola Magotti; Martha Triantafilou; Kathy Triantafilou; John D Lambris; George Hajishengallis
Journal:  Sci Signal       Date:  2010-02-16       Impact factor: 8.192

Review 7.  Mechanisms of evasion of complement by Porphyromonas gingivalis.

Authors:  Jennifer M Slaney; Michael A Curtis
Journal:  Front Biosci       Date:  2008-01-01

Review 8.  Rheumatoid arthritis and the complement system.

Authors:  Marcin Okroj; Dick Heinegård; Rikard Holmdahl; Anna M Blom
Journal:  Ann Med       Date:  2007       Impact factor: 4.709

9.  Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities.

Authors:  Stephen R Coats; Jace W Jones; Christopher T Do; Pamela H Braham; Brian W Bainbridge; Thao T To; David R Goodlett; Robert K Ernst; Richard P Darveau
Journal:  Cell Microbiol       Date:  2009-06-13       Impact factor: 3.715

10.  Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent.

Authors:  Carla J C de Haas; Karin Ellen Veldkamp; Andreas Peschel; Floor Weerkamp; Willem J B Van Wamel; Erik C J M Heezius; Miriam J J G Poppelier; Kok P M Van Kessel; Jos A G van Strijp
Journal:  J Exp Med       Date:  2004-03-01       Impact factor: 14.307
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  13 in total

1.  Periostin promotes migration and osteogenic differentiation of human periodontal ligament mesenchymal stem cells via the Jun amino-terminal kinases (JNK) pathway under inflammatory conditions.

Authors:  Yi Tang; Lin Liu; Pei Wang; Donglei Chen; Ziqiang Wu; Chunbo Tang
Journal:  Cell Prolif       Date:  2017-08-23       Impact factor: 6.831

2.  A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System.

Authors:  Monika Jusko; Jan Potempa; Danuta Mizgalska; Ewa Bielecka; Miroslaw Ksiazek; Kristian Riesbeck; Peter Garred; Sigrun Eick; Anna M Blom
Journal:  J Immunol       Date:  2015-07-24       Impact factor: 5.422

Review 3.  Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention.

Authors:  Dimitrios C Mastellos; Despina Yancopoulou; Petros Kokkinos; Markus Huber-Lang; George Hajishengallis; Ali R Biglarnia; Florea Lupu; Bo Nilsson; Antonio M Risitano; Daniel Ricklin; John D Lambris
Journal:  Eur J Clin Invest       Date:  2015-03-09       Impact factor: 4.686

4.  Genetic and intervention studies implicating complement C3 as a major target for the treatment of periodontitis.

Authors:  Tomoki Maekawa; Toshiharu Abe; Evlambia Hajishengallis; Kavita B Hosur; Robert A DeAngelis; Daniel Ricklin; John D Lambris; George Hajishengallis
Journal:  J Immunol       Date:  2014-05-07       Impact factor: 5.422

Review 5.  Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches.

Authors:  George Hajishengallis; Tomoki Maekawa; Toshiharu Abe; Evlambia Hajishengallis; John D Lambris
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

Review 6.  Mechanisms of Bone Resorption in Periodontitis.

Authors:  Stefan A Hienz; Sweta Paliwal; Saso Ivanovski
Journal:  J Immunol Res       Date:  2015-05-03       Impact factor: 4.818

Review 7.  Manipulation of Neutrophils by Porphyromonas gingivalis in the Development of Periodontitis.

Authors:  Maja Sochalska; Jan Potempa
Journal:  Front Cell Infect Microbiol       Date:  2017-05-23       Impact factor: 5.293

8.  Neutrophil mobilization by surface-glycan altered Th17-skewing bacteria mitigates periodontal pathogen persistence and associated alveolar bone loss.

Authors:  Rajendra P Settem; Kiyonobu Honma; Ashu Sharma
Journal:  PLoS One       Date:  2014-09-16       Impact factor: 3.240

Review 9.  Circadian Clock and Complement Immune System-Complementary Control of Physiology and Pathology?

Authors:  Pooja Shivshankar; Baharan Fekry; Kristin Eckel-Mahan; Rick A Wetsel
Journal:  Front Cell Infect Microbiol       Date:  2020-08-14       Impact factor: 5.293

Review 10.  Role of the Complement System in the Response to Orthopedic Biomaterials.

Authors:  Yvonne Mödinger; Graciosa Q Teixeira; Cornelia Neidlinger-Wilke; Anita Ignatius
Journal:  Int J Mol Sci       Date:  2018-10-27       Impact factor: 5.923
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