Literature DB >> 23401880

The natural product betulinic acid rapidly promotes amyloid-β fibril formation at the expense of soluble oligomers.

Matthew S Planchard1, Michael A Samel, Amit Kumar, Vijayaraghavan Rangachari.   

Abstract

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Year:  2012        PMID： 23401880      PMCID： PMC3957411          DOI： 10.1021/cn300030a

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN： 1948-7193            Impact factor:   4.418


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  38 in total

1.  Amyloid-beta(1-42) rapidly forms protofibrils and oligomers by distinct pathways in low concentrations of sodium dodecylsulfate.

Authors:  Vijayaraghavan Rangachari; Brenda D Moore; Dana Kim Reed; Leilani K Sonoda; Alexander W Bridges; Erin Conboy; David Hartigan; Terrone L Rosenberry
Journal:  Biochemistry       Date:  2007-10-02       Impact factor: 3.162

2.  Ellagic acid promotes Abeta42 fibrillization and inhibits Abeta42-induced neurotoxicity.

Authors:  Ying Feng; Shi-gao Yang; Xue-ting Du; Xi Zhang; Xiao-xia Sun; Min Zhao; Gui-yuan Sun; Rui-tian Liu
Journal:  Biochem Biophys Res Commun       Date:  2009-10-28       Impact factor: 3.575

3.  Probing the amyloid-beta(1-40) fibril environment with substituted tryptophan residues.

Authors:  Jillienne C Touchette; Laura L Williams; Deepa Ajit; Fabio Gallazzi; Michael R Nichols
Journal:  Arch Biochem Biophys       Date:  2009-12-06       Impact factor: 4.013

4.  Antioxidant activity of Bacopa monniera in rat frontal cortex, striatum and hippocampus.

Authors:  S K Bhattacharya; A Bhattacharya; A Kumar; S Ghosal
Journal:  Phytother Res       Date:  2000-05       Impact factor: 5.878

5.  Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.

Authors:  B Bohrmann; M Adrian; J Dubochet; P Kuner; F Müller; W Huber; C Nordstedt; H Döbeli
Journal:  J Struct Biol       Date:  2000-06       Impact factor: 2.867

6.  Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

Authors:  Ganesh M Shankar; Shaomin Li; Tapan H Mehta; Amaya Garcia-Munoz; Nina E Shepardson; Imelda Smith; Francesca M Brett; Michael A Farrell; Michael J Rowan; Cynthia A Lemere; Ciaran M Regan; Dominic M Walsh; Bernardo L Sabatini; Dennis J Selkoe
Journal:  Nat Med       Date:  2008-06-22       Impact factor: 53.440

7.  Rationally designed dehydroalanine (DeltaAla)-containing peptides inhibit amyloid-beta (Abeta) peptide aggregation.

Authors:  Vijayaraghavan Rangachari; Zachary S Davey; Brent Healy; Brenda D Moore; Leilani K Sonoda; Bernadette Cusack; Ghulam M Maharvi; Abdul H Fauq; Terrone L Rosenberry
Journal:  Biopolymers       Date:  2009-06       Impact factor: 2.505

Review 8.  Folding versus aggregation: polypeptide conformations on competing pathways.

Authors:  Thomas R Jahn; Sheena E Radford
Journal:  Arch Biochem Biophys       Date:  2007-06-08       Impact factor: 4.013

9.  Abeta-globulomers are formed independently of the fibril pathway.

Authors:  Gerald P Gellermann; Helga Byrnes; Andreas Striebinger; Kathrin Ullrich; Reinhold Mueller; Heinz Hillen; Stefan Barghorn
Journal:  Neurobiol Dis       Date:  2008-02-15       Impact factor: 5.996

10.  Non-esterified fatty acids generate distinct low-molecular weight amyloid-β (Aβ42) oligomers along pathway different from fibril formation.

Authors:  Amit Kumar; Rebekah L Bullard; Pritesh Patel; Lea C Paslay; Dipti Singh; Ewa A Bienkiewicz; Sarah E Morgan; Vijayaraghavan Rangachari
Journal:  PLoS One       Date:  2011-04-19       Impact factor: 3.240
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  6 in total

1.  Stability of Aβ-fibril fragments in the presence of fatty acids.

Authors:  Wenhui Xi; Elliott K Vanderford; Qinxin Liao; Ulrich H E Hansmann
Journal:  Protein Sci       Date:  2019-09-11       Impact factor: 6.725

Review 2.  Cause and consequence of Aβ - Lipid interactions in Alzheimer disease pathogenesis.

Authors:  Vijayaraghavan Rangachari; Dexter N Dean; Pratip Rana; Ashwin Vaidya; Preetam Ghosh
Journal:  Biochim Biophys Acta Biomembr       Date:  2018-03-09       Impact factor: 3.747

3.  Evaluation of betulinic acid effects on pain, memory, anxiety, catalepsy, and oxidative stress in animal model of Parkinson's disease.

Authors:  M Abrishamdar; Yaghoob Farbood; A Sarkaki; M Rashno; M Badavi
Journal:  Metab Brain Dis       Date:  2022-06-16       Impact factor: 3.584

4.  Ring-like N-fold Models of Aβ42 fibrils.

Authors:  Wenhui Xi; Ulrich H E Hansmann
Journal:  Sci Rep       Date:  2017-07-26       Impact factor: 4.379

5.  Betulinic acid inhibits pyroptosis in spinal cord injury by augmenting autophagy via the AMPK-mTOR-TFEB signaling pathway.

Authors:  Chenyu Wu; Huanwen Chen; Rong Zhuang; Haojie Zhang; Yongli Wang; Xinli Hu; Yu Xu; Jiafeng Li; Yao Li; Xiangyang Wang; Hui Xu; Wenfei Ni; Kailiang Zhou
Journal:  Int J Biol Sci       Date:  2021-03-11       Impact factor: 6.580

6.  Biophysical characteristics of lipid-induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice.

Authors:  Jhinuk Saha; Dexter N Dean; Shailendra Dhakal; Kelli A Stockmal; Sarah E Morgan; Kristy D Dillon; Munir F Adamo; Yona Levites; Vijayaraghavan Rangachari
Journal:  FASEB J       Date:  2021-02       Impact factor: 5.834
  6 in total

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