Literature DB >> 2340120

Concentration of salicylate in serum and perilymph of the chinchilla.

F A Boettcher1, B R Bancroft, R J Salvi.   

Abstract

The concentration of salicylate in serum and perilymph was measured in chinchillas after intraperitoneal administration of sodium salicylate. Serum salicylate concentration peaked 2 to 4 hours after a single injection. Clearance was approximately complete after 16 hours. The within-subject variability of serum concentration 4 hours after injection was very low. Subject weight significantly affected serum salicylate concentration, with heavier animals showing higher serum levels. The relationship of perilymph to serum salicylate concentration was approximately linear, with a high correlation between measures.

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Year:  1990        PMID： 2340120     DOI： 10.1001/archotol.1990.01870060039005

Source DB:  PubMed          Journal:  Arch Otolaryngol Head Neck Surg        ISSN： 0886-4470


  10 in total

1.  Salicylate-induced degeneration of cochlea spiral ganglion neurons-apoptosis signaling.

Authors:  L Wei; D Ding; R Salvi
Journal:  Neuroscience       Date:  2010-03-15       Impact factor: 3.590

2.  Effects of sodium salicylate on spontaneous and evoked spike rate in the dorsal cochlear nucleus.

Authors:  Lei Wei; Dalian Ding; Wei Sun; Matthew A Xu-Friedman; Richard Salvi
Journal:  Hear Res       Date:  2010-04-27       Impact factor: 3.208

3.  Effect of salicylate on KCNQ4 of the guinea pig outer hair cell.

Authors:  T Wu; P Lv; H J Kim; E N Yamoah; A L Nuttall
Journal:  J Neurophysiol       Date:  2010-02-10       Impact factor: 2.714

4.  Behavioral and Immunohistochemical Evidence for Suppressive Effects of Goshajinkigan on Salicylate-Induced Tinnitus in Rats.

Authors:  Koichi Kitano; Akinori Yamashita; Taketoshi Sugimura; Tadao Okayasu; Masaharu Sakagami; Daisuke Osaki; Tadashi Kitahara; Yasuhiko Saito
Journal:  Brain Sci       Date:  2022-04-30

5.  [Reversible hearing loss in acute salicylate intoxication].

Authors:  H Wecker; A Laubert
Journal:  HNO       Date:  2004-04       Impact factor: 1.284

Review 6.  Experimental, clinical and preventive aspects of ototoxicity.

Authors:  A A Chiodo; P W Alberti
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

Review 7.  Review: Neural Mechanisms of Tinnitus and Hyperacusis in Acute Drug-Induced Ototoxicity.

Authors:  Richard Salvi; Kelly Radziwon; Senthilvelan Manohar; Ben Auerbach; Dalian Ding; Xiaopeng Liu; Condon Lau; Yu-Chen Chen; Guang-Di Chen
Journal:  Am J Audiol       Date:  2021-01-19       Impact factor: 1.636

8.  Characterizing the Access of Cholinergic Antagonists to Efferent Synapses in the Inner Ear.

Authors:  Choongheon Lee; Anjali K Sinha; Kenneth Henry; Anqi W Walbaum; Peter A Crooks; Joseph C Holt
Journal:  Front Neurosci       Date:  2021-12-14       Impact factor: 4.677

9.  Testing the Central Gain Model: Loudness Growth Correlates with Central Auditory Gain Enhancement in a Rodent Model of Hyperacusis.

Authors:  Benjamin D Auerbach; Kelly Radziwon; Richard Salvi
Journal:  Neuroscience       Date:  2018-10-05       Impact factor: 3.590

10.  Salicylate-induced auditory perceptual disorders and plastic changes in nonclassical auditory centers in rats.

Authors:  Guang-Di Chen; Kelly E Radziwon; Nina Kashanian; Senthilvelan Manohar; Richard Salvi
Journal:  Neural Plast       Date:  2014-05-07       Impact factor: 3.599
  10 in total

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