Literature DB >> 23401175

Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation.

Elias Akoury1, Marcus Pickhardt, Michal Gajda, Jacek Biernat, Eckhard Mandelkow, Markus Zweckstetter.   

Abstract

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Year:  2013        PMID： 23401175     DOI： 10.1002/anie.201208290

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  45 in total

Review 1.  Cellular factors modulating the mechanism of tau protein aggregation.

Authors:  Sarah N Fontaine; Jonathan J Sabbagh; Jeremy Baker; Carlos R Martinez-Licha; April Darling; Chad A Dickey
Journal:  Cell Mol Life Sci       Date:  2015-02-11       Impact factor: 9.261

2.  Alternative conformations of the Tau repeat domain in complex with an engineered binding protein.

Authors:  Clara S R Grüning; Ewa A Mirecka; Antonia N Klein; Eckhard Mandelkow; Dieter Willbold; Stephen F Marino; Matthias Stoldt; Wolfgang Hoyer
Journal:  J Biol Chem       Date:  2014-06-25       Impact factor: 5.157

3.  Remodeling of the conformational ensemble of the repeat domain of tau by an aggregation enhancer.

Authors:  Elias Akoury; Marco D Mukrasch; Jacek Biernat; Katharina Tepper; Valery Ozenne; Eckhard Mandelkow; Martin Blackledge; Markus Zweckstetter
Journal:  Protein Sci       Date:  2016-03-24       Impact factor: 6.725

Review 4.  Structure and mechanism of action of tau aggregation inhibitors.

Authors:  Katryna Cisek; Grace L Cooper; Carol J Huseby; Jeff Kuret
Journal:  Curr Alzheimer Res       Date:  2014       Impact factor: 3.498

5.  Inhibition of Both Hsp70 Activity and Tau Aggregation in Vitro Best Predicts Tau Lowering Activity of Small Molecules.

Authors:  Mackenzie D Martin; Jeremy D Baker; Amirthaa Suntharalingam; Bryce A Nordhues; Lindsey B Shelton; Dali Zheng; Jonathan J Sabbagh; Timothy A J Haystead; Jason E Gestwicki; Chad A Dickey
Journal:  ACS Chem Biol       Date:  2016-05-26       Impact factor: 5.100

6.  Structural determinants of Tau aggregation inhibitor potency.

Authors:  Kelsey N Schafer; Katryna Cisek; Carol J Huseby; Edward Chang; Jeff Kuret
Journal:  J Biol Chem       Date:  2013-09-26       Impact factor: 5.157

7.  An ATR-FTIR Sensor Unraveling the Drug Intervention of Methylene Blue, Congo Red, and Berberine on Human Tau and Aβ.

Authors:  Jonas Schartner; Andreas Nabers; Brian Budde; Julia Lange; Nina Hoeck; Jens Wiltfang; Carsten Kötting; Klaus Gerwert
Journal:  ACS Med Chem Lett       Date:  2017-06-11       Impact factor: 4.345

Review 8.  Therapeutic strategies for the treatment of tauopathies: Hopes and challenges.

Authors:  Mansi R Khanna; Jane Kovalevich; Virginia M-Y Lee; John Q Trojanowski; Kurt R Brunden
Journal:  Alzheimers Dement       Date:  2016-10       Impact factor: 21.566

9.  Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.

Authors:  Cliona Stack; Shari Jainuddin; Ceyhan Elipenahli; Meri Gerges; Natalia Starkova; Anatoly A Starkov; Mariona Jové; Manuel Portero-Otin; Nathalie Launay; Aurora Pujol; Navneet Ammal Kaidery; Bobby Thomas; Davide Tampellini; M Flint Beal; Magali Dumont
Journal:  Hum Mol Genet       Date:  2014-02-20       Impact factor: 6.150

Review 10.  Interactions between Microtubule-Associated Protein Tau (MAPT) and Small Molecules.

Authors:  Jennifer N Rauch; Steven H Olson; Jason E Gestwicki
Journal:  Cold Spring Harb Perspect Med       Date:  2017-07-05       Impact factor: 6.915
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