Literature DB >> 23401040

Fabrication of chitosan nanoparticles with aggregation-induced emission characteristics and their applications in long-term live cell imaging.

Min Li1, Yuning Hong, Zhengke Wang, Sijie Chen, Meng Gao, Ryan T K Kwok, Wei Qin, Jacky W Y Lam, Qichang Zheng, Ben Zhong Tang.   

Abstract

Chitosan with tetraphenylethene pendants (TPE-CS) are synthesized by reaction between amine and isothiocyanate groups of chitosan and tetraphenylethene (TPE), respectively. Nanoparticles of TPE-CS (TPE-CS NPs) are fabricated by ionic gelation method. The NPs are uniform in size, spherical in shape, monodispersed, and positive in surface charge. The suspension of TPE-CS NPs emits strong blue fluorescence under photoexcitation due to the aggregation-induced emission characteristics of the TPE moieties. The NPs can be internalized into cytoplasm through endocytosis pathway and retain inside the live cells to image the cells. Cytotoxicity assay reveals that TPE-CS NPs are cytocompatible and thus can be used for long-term live cell imaging.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2013        PMID： 23401040     DOI： 10.1002/marc.201200760

Source DB:  PubMed          Journal:  Macromol Rapid Commun        ISSN： 1022-1336            Impact factor:   5.734


  8 in total

Review 1.  Aggregation-Induced Emission Fluorescent Gels: Current Trends and Future Perspectives.

Authors:  Javad Tavakoli; Amin Jamshidi Ghahfarokhi; Youhong Tang
Journal:  Top Curr Chem (Cham)       Date:  2021-02-05

2.  Mechanism of dynamic near-infrared fluorescence cholangiography of extrahepatic bile ducts and applications in detecting bile duct injuries using indocyanine green in animal models.

Authors:  Yang Gao; Min Li; Zi-Fang Song; Le Cui; Bi-Rong Wang; Xiao-Ding Lou; Tao Zhou; Yong Zhang; Qi-Chang Zheng
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2017-02-22

Review 3.  Chitosan-Based Nanocomposite Polymeric Membranes for Water Purification-A Review.

Authors:  Angela Spoială; Cornelia-Ioana Ilie; Denisa Ficai; Anton Ficai; Ecaterina Andronescu
Journal:  Materials (Basel)       Date:  2021-04-21       Impact factor: 3.623

4.  Chitosan-based intelligent theragnosis nanocomposites enable pH-sensitive drug release with MR-guided imaging for cancer therapy.

Authors:  Eun-Kyung Lim; Warayuth Sajomsang; Yuna Choi; Eunji Jang; Hwunjae Lee; Byunghoon Kang; Eunjung Kim; Seungjoo Haam; Jin-Suck Suh; Sang Jeon Chung; Yong-Min Huh
Journal:  Nanoscale Res Lett       Date:  2013-11-08       Impact factor: 4.703

Review 5.  AIEgen-Based Fluorescent Nanomaterials: Fabrication and Biological Applications.

Authors:  Hui Gao; Xin Zhao; Sijie Chen
Journal:  Molecules       Date:  2018-02-14       Impact factor: 4.411

6.  Theranostic Nanodots with Aggregation-Induced Emission Characteristic for Targeted and Image-Guided Photodynamic Therapy of Hepatocellular Carcinoma.

Authors:  Yang Gao; Qi Chang Zheng; Shidang Xu; Youyong Yuan; Xiang Cheng; Shuai Jiang; Qihong Yu; Zifang Song; Bin Liu; Min Li
Journal:  Theranostics       Date:  2019-02-12       Impact factor: 11.556

7.  Dual-Targeting Nanoparticle-Mediated Gene Therapy Strategy for Hepatocellular Carcinoma by Delivering Small Interfering RNA.

Authors:  Qi Chang Zheng; Shuai Jiang; Yu Zhe Wu; Dan Shang; Yong Zhang; Shao Bo Hu; Xiang Cheng; Chen Zhang; Ping Sun; Yang Gao; Zi Fang Song; Min Li
Journal:  Front Bioeng Biotechnol       Date:  2020-06-10

8.  Preparation and Characterization of Chitosan/TiO2 Composite Membranes as Adsorbent Materials for Water Purification.

Authors:  Angela Spoială; Cornelia-Ioana Ilie; Georgiana Dolete; Alexa-Maria Croitoru; Vasile-Adrian Surdu; Roxana-Doina Trușcă; Ludmila Motelica; Ovidiu-Cristian Oprea; Denisa Ficai; Anton Ficai; Ecaterina Andronescu; Lia-Mara Dițu
Journal:  Membranes (Basel)       Date:  2022-08-20
  8 in total

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