Mohammad-Reza Sheikh Sajjadieh1, Larisa V Kuznetsova, Vadim B Bojenko. 1. Department of Clinical Immunology & Allergology, National Medical Academy for Post Graduate Education, Kiev, Ukraine ; Ukrainian Specialized Dispensaries of Radiation Defend Population, Kiev, Ukraine.
Abstract
OBJECTIVE: Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora. METHODS: Our study included 75 rural children aged 4-18 years, who lived in contaminated area exposed to natural environmental radiation with clinical symptoms of irritable bowel syndrome and 20 healthy urban participants aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples. FINDINGS: Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects (81.3%) was significantly less than in control group. CONCLUSION: We investigated alternation of the intestinal microbiota affected by ionizing radiation in children with clinical symptoms of irritable bowel syndrome.
OBJECTIVE: Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora. METHODS: Our study included 75 rural children aged 4-18 years, who lived in contaminated area exposed to natural environmental radiation with clinical symptoms of irritable bowel syndrome and 20 healthy urban participants aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples. FINDINGS: Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects (81.3%) was significantly less than in control group. CONCLUSION: We investigated alternation of the intestinal microbiota affected by ionizing radiation in children with clinical symptoms of irritable bowel syndrome.
Authors: C De Simone; A Ciardi; A Grassi; S Lambert Gardini; S Tzantzoglou; V Trinchieri; S Moretti; E Jirillo Journal: Immunopharmacol Immunotoxicol Date: 1992 Impact factor: 2.730
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