Literature DB >> 23400046

A prospective Cross-sectional Cohort Assessment of Health, Physical, and Behavioral Problems in Autism Spectrum Disorders.

David A Geier1, Janet K Kern, Mark R Geier.   

Abstract

OBJECTIVES: Autism spectrum disorder (ASD) is diagnostically defined by impaired socialization/communication and stereotypical behaviors. Health, physical, and behavioral problems have also been described in subjects diagnosed with an ASD, but have usually been examined in isolation. The purpose of the present study was to for the first time, systematically and quantitatively, examines health, physical and behavioral problems in a cohort of subjects diagnosed with an ASD.
MATERIALS AND METHODS: A prospective cross-sectional ASD cohort (n=54) was evaluated for health, physical, and behavioral symptoms derived from parentally completed Autism Treatment Evaluation Checklist (ATEC) forms. The study protocol received Institutional Review Board (IRB) approval from Liberty IRB, Inc (Deland, FL). OUTCOMES: The results showed the following occurrence of symptoms among study participants: gastrointestinal disturbances=48%, incontinence=57%, sleep problems=57%, eating disorders=94%, hyperactivity=67%, lethargy=26%, sensory processing problems=85%, anxiety/fear=74%, behavioral problems=89%, and obsessive-compulsive behaviors=92%. Of all of the areas examined, eating problems, behavioral problems, and obsessive-compulsive behaviors, were reported by the parents to be the most serious and problematic.
CONCLUSIONS: The present findings, taken together with previous research, suggest that subjects diagnosed with an ASD have significant health, physical, and behavioral problems beyond the symptoms evaluated in the diagnostic criteria used to diagnosis an ASD. The present findings also suggest the ATEC provides an economical means for healthcare providers to identify health, physical, and behavioral problems in subjects diagnosed with an ASD.

Entities:  

Keywords:  ASDs; ATEC; Asperger's; CARS; PDD-NOS; autistic

Year:  2012        PMID: 23400046      PMCID: PMC3566881     

Source DB:  PubMed          Journal:  Maedica (Buchar)        ISSN: 1841-9038


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1.  A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States.

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3.  Validating the Revised Illness Perception Questionnaire as a Measure of Parent Perceptions of Autism Spectrum Disorder.

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4.  Incontinence in autism spectrum disorder: a systematic review.

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5.  Measles-mumps-rubella vaccination timing and autism among young African American boys: a reanalysis of CDC data.

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6.  The short-term effects of transcranial direct current stimulation on electroencephalography in children with autism: a randomized crossover controlled trial.

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7.  Effect of anodal transcranial direct current stimulation on autism: a randomized double-blind crossover trial.

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Review 8.  Thimerosal exposure and the role of sulfation chemistry and thiol availability in autism.

Authors:  Janet K Kern; Boyd E Haley; David A Geier; Lisa K Sykes; Paul G King; Mark R Geier
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10.  Evidence of neurodegeneration in autism spectrum disorder.

Authors:  Janet K Kern; David A Geier; Lisa K Sykes; Mark R Geier
Journal:  Transl Neurodegener       Date:  2013-08-08       Impact factor: 8.014

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