OBJECTIVES: This study intends to analyze some statistical data concerning Cervical Intraepithelial Neoplasia diagnosed in our hospital. MATERIAL AND METHODS: Our study concerning the incidence of Cervical Intraepithelial Neoplasia (CIN) covers the 2000-2009 time-span, the data being collected from the Histopathology Exams (HPE) registers. RESULTS: During this period, CIN lesions were discovered in 1256 cases and Cervical Intraglandular Dysplasia (CIGD) in 53 cases. CIN I, CIN II and CIN III lesions represented 65.92%(828 cases), 19.67% (247 cases), and 14.41% (181 cases) of the total CIN cases, respectively. There were 26 cases combined with cervical carcinoma (2.07% of all CIN cases, 3.56% of the 731 cervical cancer cases). The mean patients' age was 44.65± 9.83 years for all cervical dysplasia cases, 44.58± 9.75 years for all CIN cases, 43.81±9.22, 46.50±10.17, and 45.46±11.05 years for CIN I, CIN II, and CIN III, respectively, and 46.45 ± 11.63 years for CIGD. The t-test revealed the following significant differences: all cases versus CIN I (p<0.05) and CIN II (p<0.01), CIGD versus CIN I (p<0.05), all cases versus CIN II (p<0.01), CIN I versus CIN II (p<0.0001) and versus CIN III (p<0.05). The mean age of the 731 cervical cancer cases diagnosed in our hospital during that same period was 52.94±12.96 years,and it was statistically significantly different from the mean ages of patients with CIN I, II and III (p <0.00000001) and with CIGD (p<0.0005). CONCLUSIONS: Early detection of CIN is of utmost importance for preventing cervical cancer, a serious and frequent health problem in Romania.
OBJECTIVES: This study intends to analyze some statistical data concerning Cervical Intraepithelial Neoplasia diagnosed in our hospital. MATERIAL AND METHODS: Our study concerning the incidence of Cervical Intraepithelial Neoplasia (CIN) covers the 2000-2009 time-span, the data being collected from the Histopathology Exams (HPE) registers. RESULTS: During this period, CIN lesions were discovered in 1256 cases and Cervical Intraglandular Dysplasia (CIGD) in 53 cases. CIN I, CIN II and CIN III lesions represented 65.92%(828 cases), 19.67% (247 cases), and 14.41% (181 cases) of the total CIN cases, respectively. There were 26 cases combined with cervical carcinoma (2.07% of all CIN cases, 3.56% of the 731 cervical cancer cases). The mean patients' age was 44.65± 9.83 years for all cervical dysplasia cases, 44.58± 9.75 years for all CIN cases, 43.81±9.22, 46.50±10.17, and 45.46±11.05 years for CIN I, CIN II, and CIN III, respectively, and 46.45 ± 11.63 years for CIGD. The t-test revealed the following significant differences: all cases versus CIN I (p<0.05) and CIN II (p<0.01), CIGD versus CIN I (p<0.05), all cases versus CIN II (p<0.01), CIN I versus CIN II (p<0.0001) and versus CIN III (p<0.05). The mean age of the 731 cervical cancer cases diagnosed in our hospital during that same period was 52.94±12.96 years,and it was statistically significantly different from the mean ages of patients with CIN I, II and III (p <0.00000001) and with CIGD (p<0.0005). CONCLUSIONS: Early detection of CIN is of utmost importance for preventing cervical cancer, a serious and frequent health problem in Romania.
Authors: A J Robertson; J M Anderson; J S Beck; R A Burnett; S R Howatson; F D Lee; A M Lessells; K M McLaren; S M Moss; J G Simpson Journal: J Clin Pathol Date: 1989-03 Impact factor: 3.411
Authors: Susanne Kjaer; Estrid Høgdall; Kirsten Frederiksen; Christian Munk; Adriaan van den Brule; Edith Svare; Chris Meijer; Attilla Lorincz; Thomas Iftner Journal: Cancer Res Date: 2006-10-23 Impact factor: 12.701
Authors: Mark Schiffman; Rolando Herrero; Rob Desalle; Allan Hildesheim; Sholom Wacholder; Ana Cecilia Rodriguez; Maria C Bratti; Mark E Sherman; Jorge Morales; Diego Guillen; Mario Alfaro; Martha Hutchinson; Thomas C Wright; Diane Solomon; Zigui Chen; John Schussler; Philip E Castle; Robert D Burk Journal: Virology Date: 2005-06-20 Impact factor: 3.616
Authors: M D Greenberg; R Reid; M Schiffman; M J Campion; S L Precop; N R Berman; T Zemlo; M Husain; G Herman; K H Omato; A T Lorincz Journal: J Low Genit Tract Dis Date: 1999-04 Impact factor: 1.925
Authors: Michael Sindos; Daniel Ndisang; Narendra Pisal; Carl Chow; Albert Singer; David S Latchman Journal: Gynecol Oncol Date: 2003-08 Impact factor: 5.482