Literature DB >> 23399297

Outcomes after ultrasound-guided platelet-rich plasma injections for chronic tendinopathy: a multicenter, retrospective review.

Kenneth Mautner1, Ricardo E Colberg, Gerard Malanga, Joanne P Borg-Stein, Kimberly G Harmon, Aisha S Dharamsi, Samuel Chu, Paul Homer.   

Abstract

OBJECTIVE: To determine whether ultrasound-guided platelet-rich plasma (PRP) injections are an effective treatment for chronic tendinopathies.
DESIGN: A retrospective, cross-sectional survey.
SETTING: Four academic sports medicine centers from across the United States. PATIENTS: A total of 180 men and women between the ages of 18 and 75 years who received ultrasound-guided PRP injections for tendinopathy refractory to conventional treatments.
INTERVENTIONS: Survey on satisfaction and functional outcome. MAIN OUTCOME MEASUREMENTS: Perceived improvement in symptoms at least 6 months after treatment, perceived change in visual analog scale score, assessment of functional pain, and overall satisfaction.
RESULTS: On average, patients were 48 years old, had symptoms for a median of 18 months before treatment, and answered the survey on average 15 months after treatment. Overall, 82% of patients indicated moderate to complete improvement in symptoms. The most common injection sites were the lateral epicondyle, Achilles, and patellar tendons. Other sites treated included the rotator cuff, hamstring, gluteus medius, and medial epicondyle, among others. Furthermore, 60% of patients received only 1 injection, 30% received 2 injections, and 10% received 3 or more injections. Patients' perceived decrease in visual analog scale score was 75%, from 7.0 ± 1.8 to 1.8 ± 2.0 (-5.2, SD 2.7, 95% confidence interval -5.65 to -4.86, P < .0001). In addition, at follow-up, 95% of patients reported having no pain at rest that disrupted their activities of daily living and 68% reported no pain during activities. A total of 85% of patients were satisfied with the procedure.
CONCLUSIONS: In this retrospective study, in which we evaluated administration of PRP for chronic tendinopathy, we found that the majority of patients reported a moderate (>50%) improvement in pain symptoms.
Copyright © 2013 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

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Year:  2013        PMID: 23399297     DOI: 10.1016/j.pmrj.2012.12.010

Source DB:  PubMed          Journal:  PM R        ISSN: 1934-1482            Impact factor:   2.298


  35 in total

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2.  Lower Extremity Injury Patterns in Elite Ballet Dancers: Ultrasound/MRI Imaging Features and an Institutional Overview of Therapeutic Ultrasound Guided Percutaneous Interventions.

Authors:  Razia Rehmani; Yoshimi Endo; Phillip Bauman; William Hamilton; Hollis Potter; Ronald Adler
Journal:  HSS J       Date:  2015-07-10

Review 3.  Expert opinion: diagnosis and treatment of proximal hamstring tendinopathy.

Authors:  Lasse Lempainen; Kristian Johansson; Ingo J Banke; Juha Ranne; Keijo Mäkelä; Janne Sarimo; Pekka Niemi; Sakari Orava
Journal:  Muscles Ligaments Tendons J       Date:  2015-03-27

Review 4.  Augmenting tendon and ligament repair with platelet-rich plasma (PRP).

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Journal:  Muscles Ligaments Tendons J       Date:  2013-08-11

Review 5.  The use of platelet-rich plasma to augment conservative and surgical treatment of hip and pelvic disorders.

Authors:  Matthew J Kraeutler; Tigran Garabekyan; Omer Mei-Dan
Journal:  Muscles Ligaments Tendons J       Date:  2016-12-21

Review 6.  Myths and Facts of In-Office Regenerative Procedures for Tendinopathy.

Authors:  Alyssa Neph; Kentaro Onishi; James H-C Wang
Journal:  Am J Phys Med Rehabil       Date:  2019-06       Impact factor: 2.159

Review 7.  Considerations for the use of platelet-rich plasma in orthopedics.

Authors:  Taralyn M McCarrel; Nathan A Mall; Andrew S Lee; Brian J Cole; Davietta C Butty; Lisa A Fortier
Journal:  Sports Med       Date:  2014-08       Impact factor: 11.136

Review 8.  Platelet-rich plasma in tendon-related disorders: results and indications.

Authors:  Giuseppe Filardo; Berardo Di Matteo; Elizaveta Kon; Giulia Merli; Maurilio Marcacci
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-09-24       Impact factor: 4.342

9.  Platelet-rich plasma injections for the treatment of refractory Achilles tendinopathy: results at 4 years.

Authors:  Giuseppe Filardo; Elizaveta Kon; Berardo Di Matteo; Alessandro Di Martino; Giulia Tesei; Patrizia Pelotti; Annarita Cenacchi; Maurilio Marcacci
Journal:  Blood Transfus       Date:  2014-06-19       Impact factor: 3.443

10.  Sonoelastography shows that Achilles tendons with insertional tendinopathy are harder than asymptomatic tendons.

Authors:  Qi Zhang; Yehua Cai; Yinghui Hua; Jun Shi; Yuanyuan Wang; Yi Wang
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-06-24       Impact factor: 4.342

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