Literature DB >> 23397438

On the reliability of quantitation of biological effect in drug-interceptor-DNA systems.

Anatoly S Buchelnikov1, Vladyslav P Evstigneev, Leticia E Rodríguez Oropeza, Maxim P Evstigneev.   

Abstract

Relative insensitivity of theoretical estimation of biological effect in drug-interceptor-DNA systems is found with respect to variation of parameters of quasiphysiological conditions. The "inertness" of the biological response, in part, justifies the use of parameters of intermolecular interaction, derived from independent physicochemical experiments, in estimation of relative biological effect in the theory of interceptor/protector action.

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Year:  2013        PMID： 23397438     DOI： 10.1007/s00249-013-0893-1

Source DB:  PubMed          Journal:  Eur Biophys J        ISSN： 0175-7571            Impact factor:   1.733


  14 in total

1.  Quantitation of the molecular mechanisms of biological synergism in a mixture of DNA-acting aromatic drugs.

Authors:  M P Evstigneev; A O Lantushenko; V P Evstigneev; Yu V Mykhina; D B Davies
Journal:  Biophys Chem       Date:  2007-11-12       Impact factor: 2.352

2.  Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin.

Authors:  Monika Pietrzak; H Dorota Halicka; Zbigniew Wieczorek; Jolanta Wieczorek; Zbigniew Darzynkiewicz
Journal:  Biophys Chem       Date:  2008-03-30       Impact factor: 2.352

3.  General analysis of competitive binding in drug-interceptor-DNA systems.

Authors:  A S Buchelnikov; A A Hernandez Santiago; M Gonzalez Flores; R Vazquez Ramirez; D B Davies; M P Evstigneev
Journal:  Eur Biophys J       Date:  2012-01-03       Impact factor: 1.733

4.  The molecular basis for complexation of adriamycin with flavin mononucleotide and flavin adenine dinucleotide.

Authors:  E D Kharasch; R F Novak
Journal:  Arch Biochem Biophys       Date:  1981-11       Impact factor: 4.013

5.  Complexation of biologically active aromatic compounds with DNA in the presence of theophylline.

Authors:  A A Hernandez Santiago; D D Andrejuk; A M Cervantes Tavera; D B Davies; M P Evstigneev
Journal:  J Biol Phys       Date:  2009-01-10       Impact factor: 1.365

6.  Natural compounds in the human diet and their ability to bind mutagens prevents DNA-mutagen intercalation.

Authors:  Adam Osowski; Monika Pietrzak; Zbigniew Wieczorek; Jolanta Wieczorek
Journal:  J Toxicol Environ Health A       Date:  2010

7.  Complexation of norfloxacin with DNA in the presence of caffeine.

Authors:  M P Evstigneev; K A Rybakova; D B Davies
Journal:  Biophys Chem       Date:  2006-02-07       Impact factor: 2.352

8.  Caffeine, pentoxifylline and theophylline form stacking complexes with IQ-type heterocyclic aromatic amines.

Authors:  Anna Woziwodzka; Anna Gwizdek-Wiśniewska; Jacek Piosik
Journal:  Bioorg Chem       Date:  2010-11-16       Impact factor: 5.275

9.  Caffeine dissociates complexes between DNA and intercalating dyes: application for bleaching fluorochrome-stained cells for their subsequent restaining and analysis by laser scanning cytometry.

Authors:  E Bedner; L Du; F Traganos; Z Darzynkiewicz
Journal:  Cytometry       Date:  2001-01-01

10.  The "interceptor" properties of chlorophyllin measured within the three-component system: intercalator-DNA-chlorophyllin.

Authors:  Monika Pietrzak; Zbigniew Wieczorek; Jolanta Wieczorek; Zbigniew Darzynkiewicz
Journal:  Biophys Chem       Date:  2006-04-06       Impact factor: 2.352
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