Literature DB >> 23396992

Case report: Inflammatory myofibroblastic tumor of pancreatic origin in a patient with down syndrome: The role of diagnostic ultrasound.

M Colangelo1, D Di Renzo, A Persico, P Lelli Chiesa.   

Abstract

INTRODUCTION: Inflammatory myofibroblastic tumor (IMT) is a benign solid tumor of uncertain etiology.
MATERIALS AND METHODS: We report a case of a 4-year-old Down syndrome affected child, who had a pancreatic mass identified by ultrasonography (US) and confirmed by computed tomography (CT).
RESULTS: Monitoring of IMT was performed by serial US studies, and at follow-up after 4 years there was no relapse. DISCUSSION: As radical removal of the lesion was not possible, the patient was successfully treated with nonsteroidal anti-inflammatory drugs (NSAIDs). It was decided to monitor the lesion by serial US in order to reduce the number of CT examinations and thereby avoid excessive exposure to ionizing radiation. It is widely reported in the literature that repeated CT scans are associated with increased exposure to radiation which may cause cancer, a fact which should not be overlooked in children.

Entities:  

Keywords:  Computed tomography (CT); Down's syndrome; Inflammatory myofibroblastic tumor (IMT); Nonsteroidal anti-inflammatory drugs (NSAIDs)

Year:  2010        PMID: 23396992      PMCID: PMC3558039          DOI: 10.1016/j.jus.2010.11.003

Source DB:  PubMed          Journal:  J Ultrasound        ISSN: 1876-7931


  6 in total

1.  The rationale for nonsteroidal anti-inflammatory drug therapy for inflammatory myofibroblastic tumors: a Children's Oncology Group study.

Authors:  Harry Applebaum; Mark W Kieran; Timothy P Cripe; Cheryl M Coffin; Margaret H Collins; Arja Kaipainen; Andrea Laforme; Robert C Shamberger
Journal:  J Pediatr Surg       Date:  2005-06       Impact factor: 2.545

2.  Frequent presence of the Epstein-Barr virus in inflammatory pseudotumor.

Authors:  D A Arber; O W Kamel; M van de Rijn; R E Davis; L J Medeiros; E S Jaffe; L M Weiss
Journal:  Hum Pathol       Date:  1995-10       Impact factor: 3.466

3.  SPECT imaging of the spleen in inflammatory pseudotumor. Correlation with ultrasound, CT, and MRI.

Authors:  M Glazer; V Sagar
Journal:  Clin Nucl Med       Date:  1993-06       Impact factor: 7.794

4.  Pancreatic pseudotumor in an 11-year-old child: imaging findings.

Authors:  M B McClain; E M Burton; D S Day
Journal:  Pediatr Radiol       Date:  2000-09

5.  Pancreatic inflammatory pseudotumour: an uncommon childhood lesion mimicking a malignant tumour.

Authors:  G Morris-Stiff; G M Vujanić; A Al-Wafi; J Lari
Journal:  Pediatr Surg Int       Date:  1998-01       Impact factor: 1.827

6.  Inflammatory myofibroblastic tumor of the pancreas: a case report of 2 pediatric cases--steroids or surgery?

Authors:  Haitham Dagash; Cheryl Koh; Marta Cohen; Alan Sprigg; Jenny Walker
Journal:  J Pediatr Surg       Date:  2009-09       Impact factor: 2.545

  6 in total
  1 in total

1.  Inflammatory myofibroblastic tumor of the gallbladder: imaging aspects.

Authors:  Radu Badea; Antonia Alexandra Veres; Vasile Andreica; Cosmin Caraiani; Nadim Al-Hajjar; Roxana Sechel; Liliana Chiorean
Journal:  J Med Ultrason (2001)       Date:  2014-08-15       Impact factor: 1.314

  1 in total

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