| Literature DB >> 23395162 |
Clifford D L Folmes1, Sungjo Park, Andre Terzic.
Abstract
Metabolic plasticity is increasingly postulated to be vital in the transition between stemness maintenance and lineage specification. Knobloch et al. (2012) now demonstrate that regulation of lipogenesis by fatty acid synthase and Spot14-dependent malonyl-CoA supply determines the proliferative activity of resident neural stem cells, contributing to adult neurogenesis.Entities:
Year: 2013 PMID: 23395162 DOI: 10.1016/j.cmet.2013.01.010
Source DB: PubMed Journal: Cell Metab ISSN: 1550-4131 Impact factor: 27.287