The value of tumor-associated tissue inflammatory reaction in primary superficial bladder cancer.

The data of 92 patients who entered the prospective study between 1980 and 1982 were evaluable. The prevalence of tumor-associated tissue inflammatory reaction according to the tumorparameters stage, grade, multiplicity, tumor-weight and concomitant urothelial changes in primary superficial transitional cell cancer was estimated. Using high power field on the microscope tumor-associated cells were classified as lymphocytes, plasma cells, mast cells and eosinophils by morphological criteria. Recurrence rate, tumor progression and survival rate were evaluated for the group with tumor-associated cell infiltration and compared with the data of the group without any tumor-associated inflammatory reaction. According to recurrence rate, progression rate and survival rate there was a tendency to better prognosis for tumors with associated inflammatory reaction but this could not be proven by statistical analyses.