Literature DB >> 23394093

From NAFLD to NASH and HCC: pathogenetic mechanisms and therapeutic insights.

Samuele De Minicis1, Chris Day, Gianluca Svegliati-Baroni.   

Abstract

NAFLD is the most common liver disease worldwide but it is the potential evolution to cirrhosis and hepatocellular carcinoma (HCC) that makes NAFLD of such clinical importance. The current work provides an overview of the main mechanims and potential therapeutical insights involved in NAFLD, NASH, fibrosis and HCC progression.

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Year:  2013        PMID： 23394093

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN： 1381-6128            Impact factor:   3.116


  29 in total

1.  Comments on "NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis".

Authors:  Guangbing Li; Li Yuan; Jun Liu; Haitao Zhao
Journal:  Hepatobiliary Surg Nutr       Date:  2016-12       Impact factor: 7.293

2.  Bioinformatics Analysis of Key Differentially Expressed Genes in Nonalcoholic Fatty Liver Disease Mice Models.

Authors:  Chao Hou; Wenwen Feng; Shan Wei; Yulin Wang; Xiaoyi Xu; Jin Wei; Ziliang Ma; Yongsheng Du; Jialin Guo; Yu He; Fanyun Kong; Renxian Tang; Kuiyang Zheng
Journal:  Gene Expr       Date:  2018-08-22

3.  Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease.

Authors:  Vanessa Souza-Mello
Journal:  World J Hepatol       Date:  2015-05-18

4.  Gut microbiota, fatty liver disease, and hepatocellular carcinoma.

Authors:  Huikuan Chu; Brandon Williams; Bernd Schnabl
Journal:  Liver Res       Date:  2018-02-21

Review 5.  MicroRNAs as controlled systems and controllers in non-alcoholic fatty liver disease.

Authors:  Nadia Panera; Daniela Gnani; Annalisa Crudele; Sara Ceccarelli; Valerio Nobili; Anna Alisi
Journal:  World J Gastroenterol       Date:  2014-11-07       Impact factor: 5.742

6.  Liver Resection for Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: a Multicenter Propensity Matching Analysis with HBV-HCC.

Authors:  Tian Yang; Lun-Yang Hu; Zhen-Li Li; Kai Liu; Han Wu; Hao Xing; Wan Yee Lau; Timothy M Pawlik; Yong-Yi Zeng; Ya-Hao Zhou; Wei-Min Gu; Hong Wang; Ting-Hao Chen; Jun Han; Chao Li; Ming-Da Wang; Meng-Chao Wu; Feng Shen
Journal:  J Gastrointest Surg       Date:  2019-01-07       Impact factor: 3.452

7.  Obeticholic acid improves adipose morphometry and inflammation and reduces steatosis in dietary but not metabolic obesity in mice.

Authors:  Fahrettin Haczeyni; Laurence Poekes; Hans Wang; Auvro R Mridha; Vanessa Barn; W Geoffrey Haigh; George N Ioannou; Matthew M Yeh; Isabelle A Leclercq; Narcissus C Teoh; Geoffrey C Farrell
Journal:  Obesity (Silver Spring)       Date:  2016-11-02       Impact factor: 5.002

Review 8.  Hepatocellular carcinoma and non-alcoholic steatohepatitis: The state of play.

Authors:  Bérénice Charrez; Liang Qiao; Lionel Hebbard
Journal:  World J Gastroenterol       Date:  2016-02-28       Impact factor: 5.742

9.  Coffee consumption in NAFLD patients with lower insulin resistance is associated with lower risk of severe fibrosis.

Authors:  Kiran Bambha; Laura A Wilson; Aynur Unalp; Rohit Loomba; Brent A Neuschwander-Tetri; Elizabeth M Brunt; Nathan M Bass
Journal:  Liver Int       Date:  2013-11-24       Impact factor: 5.828

10.  NKp46(+) natural killer cells attenuate metabolism-induced hepatic fibrosis by regulating macrophage activation in mice.

Authors:  Annie-Carole Tosello-Trampont; Peter Krueger; Sowmya Narayanan; Susan G Landes; Norbert Leitinger; Young S Hahn
Journal:  Hepatology       Date:  2016-01-21       Impact factor: 17.425
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